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TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Electrospun matrices help regenerate skin and hair follicles using PCL and collagen scaffolds.

Active oxygen species might be involved in skin tumor growth, but their exact role is unclear.

Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.

Regulating cell death in hair follicles can help prevent hair loss and promote hair growth.

Arteannuin might work against cancer and Alzheimer's by targeting neprilysin.

Collagen XVII is important for skin aging and wound healing.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

A new MBTPS2 gene variant disrupts fat metabolism and collagen production, causing Osteogenesis imperfecta.

Finding functions for unknown GPCRs is hard but key for making new drugs.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.

A substance called compound-1 could help increase hair growth by maintaining prostaglandin levels in hair follicles.

Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.

Applying InlB321/15 to wounds sped up healing in mice.

Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.

The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Different types of stem cells and their environments are key to skin repair and maintenance.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.