83 citations
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February 1991 in “Development” This study found that Fos protein expression is closely linked to epithelial cell differentiation, particularly during cornification and cell death, with overexpression observed in keratinization-blocked mutant epidermis.
14 citations
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June 2020 in “BMC genomics” This study observed that the growth cycle of cashmere in Inner Mongolian cashmere goats consists of three phases, with genes KAP3–1, KRTAP 8–1, and KRTAP 24–1 closely correlating with this cycle.
13 citations
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February 2025 in “Nature Communications” In this study, a deep neural network model called regX was developed to prioritize driver regulators for cell state transitions by incorporating gene-level regulation and interactions, showing potential therapeutic targets in type 2 diabetes and hair follicle development when applied to single-cell multi-omics data.
12 citations
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February 2019 in “Skin research and technology” This study found that white hair fibers have lower lipid content and different water absorption dynamics compared to brown hair fibers, suggesting differences in their barrier functions.
5 citations
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January 2024 in “Advances in Pharmacological and Pharmaceutical Sciences” This review explored the biological properties of Punica granatum, noting its antioxidant, anti-inflammatory, and antimicrobial activities, and highlighted its potential as a therapeutic agent for various conditions; however, more extensive clinical trials are needed to confirm its effectiveness and safety.
October 2021 in “Journal of Investigative Dermatology” This study found that reconstructed human epidermis from infant skin is more susceptible to UV damage than that from older children, with notable changes in skin cell characteristics during the early years of life.
April 2021 in “Current Topics in Nutraceutical Research” This study found that citron seed oil promotes hair regrowth in a C57BL/6 mouse model by enhancing the transition to the growth phase, increasing hair follicle features and skin thickness, and inducing specific protein expressions that support hair regeneration.
May 2020 in “Research Square (Research Square)” This study discovered that key genes like KAP3-1 and KRTAPs are closely linked to the growth cycle of cashmere in Inner Mongolian goats, identifying March as the primary cycle's onset.
February 2020 in “Research Square (Research Square)” In this study, the researchers identified key genes, including KAP and KRTAP, that correlate with the secondary hair follicle growth cycle in Inner Mongolian cashmere goats, emphasizing March as the significant transition month.
May 2026 in “Apollo (University of Cambridge)” In this review, the authors discuss how SOX9 functions as a key regulator of epithelial cell fate and tissue repair, suggesting its role in integrating environmental signals, which could inform regenerative medicine approaches despite potential risks like fibrosis and cancer.
68 citations
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May 2013 in “The American journal of medicine” This report documents two cases of severe systemic poisoning from heavy metals after short-term use of traditional Chinese medicines for treating damaged or infected tissue.
October 2025 in “Journal of Advances in Medical and Pharmaceutical Sciences” This study reported that Neelibhringadi Kera Tailam, a traditional Ayurvedic herbal oil, contains bioactive compounds that may support hair health by stimulating growth, providing antimicrobial, antioxidant, and anti-inflammatory effects, and preventing hair loss, as evidenced by its physicochemical, phytochemical, and GC-MS analyses.
This paper examines the development of scalp cooling as a non-drug method to reduce chemotherapy-induced hair loss, addressing an emotionally challenging side effect of cancer treatment. Results are not provided in the abstract.
January 2024 in “Deleted Journal” This review synthesizes research on Thuja species, highlighting their diverse biological effects, traditional and economic uses, and various phytoconstituents, and suggests they are promising candidates for further studies to potentially develop new drugs.
January 2023 in “Ethnobotany Research and Applications” This study characterized the anatomical and phytochemical features of Viola odorata, which may assist taxonomists in species analysis and improve regulatory processes for quality assurance.
92 citations
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December 2020 in “Brain Sciences” This review discusses the potential of various Indian herbal medicines in treating cognitive impairment related to Alzheimer's disease but reports no new clinical findings; it highlights the need for further research.
52 citations
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May 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that overexpression of parathyroid hormone-related protein in mice resulted in 30–40% shorter hair due to premature transition into the catagen phase of the hair cycle.
12 citations
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September 2015 in “Drug Design Development and Therapy” This study found that the DOX derivative AD198 more effectively inhibited cell viability and induced apoptosis in canine cancer cell lines K9TCC and K9OSA compared to DOX in vitro.
July 2025 in “Phytomedicine Plus” This study reported that Cyperus rotundus L., a plant used in traditional medicine, effectively reduces hair growth with minimal side effects, showing efficacy comparable to Alexandrite laser treatments in certain cases, particularly for white hair, positioning it as a potential natural alternative to chemical depilatories.
June 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study found that a synthetic polyphenol, dimeric 1,2,4-benzenetriol (diBTO), can coat gray hair and gradually oxidize, creating a resistant brown layer similar to apple browning, which offers a practical hair dyeing solution that withstands washing and reduces the need for long dyeing sessions.
This study suggests that bioactives like Curcumin, Quercetin, and "Tulsi" may relieve chemotherapy-induced adverse drug reactions in cancer patients, potentially reducing resistance and recurrence.
April 2023 in “Journal of Investigative Dermatology” This study demonstrates that human epidermal stem cells can adapt to environmental temperature changes through mTOR signaling, and prolonged inhibition of mTORC1 supports stem cell maintenance, which may be vital for regenerative medicine.
January 2019 in “Journal of Entomology and Zoology Studies” This study observed that in Assam Hill Goats, the primary hair follicles had larger diameters and more structural associations compared to secondary follicles, especially in ruminant-age groups.
2 citations
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June 2023 in “Research in Pharmaceutical Sciences” Bhamrung-Lohit may help with inflammation and oxidation.
January 2025 in “Dermatological Reviews” This study reports that Cyperus rotundus L. (nut grass) shows promise as a natural hair removal agent, with compounds targeting hair follicles and potentially offering an alternative to chemical depilatories, demonstrated by its efficacy in clinical trials and comparable results to some laser treatments.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified distinct and diverse fibroblast populations in female scalp cells that lose their signature and identity with age, highlighting significant age-related changes, such as increased fibrosis, DNA damage, and senescence, which may affect scalp dermal support for healthy hair follicles.
April 2019 in “Journal of Drug Delivery and Therapeutics” In this study, researchers developed poly herbal shampoo formulations using natural herbs like Ashwagandha and Amla, which showed effective hair care benefits including strengthening hair growth and preventing dandruff while maintaining safe pH and foaming capacity; however, stability studies for these formulations are needed.
13 citations
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June 2020 in “International Journal of Molecular Sciences” This study found that the humanin analogue HNG significantly promoted hair growth in vitro and in vivo by prolonging the anagen phase and inhibiting hair follicle cell apoptosis in mice.
3 citations
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December 2023 in “Aging” In liver cancer cells, this study found that upregulating hsa_circ_0002980 inhibits cell proliferation, metastasis, and EMT by modulating the miR-1303/CADM2 axis, suggesting it as a potential therapeutic target.
This study found that hoof progenitor cells from fresh equine tissue have multilineage differentiation capabilities, offering insights for future progenitor cell-based hoof and dermal-epidermal tissue engineering.