research Immunohistochemical Study Assessing Stem Cell Factor Receptor C-Kit in Patients with Alopecia
People with alopecia have shorter hair follicles and more c-kit, a stem cell factor receptor, which could predict how the condition progresses.
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research Hormones and Absence Epilepsy
Stress and hormones like progesterone can affect absence seizures, but their effects change with different life stages.
research MicroRNA Control of Signal Transduction
MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.
research The Selective Androgen Receptor Modulator GTx-024 (Enobosarm) Improves Lean Body Mass and Physical Function in Healthy Elderly Men and Postmenopausal Women: Results of a Double-Blind, Placebo-Controlled Phase II Trial
Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.
research Modulation of Hair Growth with Small Molecule Agonists of the Hedgehog Signaling Pathway
Applying a special compound can promote hair growth without harmful side effects.
research 2,3,7,8-Tetrachlorodibenzo-p-dioxin Increases the Expression of Genes in the Human Epidermal Differentiation Complex and Accelerates Epidermal Barrier Formation
TCDD speeds up skin barrier formation by increasing certain gene expressions.
research Role of Anticonvulsant and Antiepileptogenic Neurosteroids in the Pathophysiology and Treatment of Epilepsy
Neurosteroids show promise for treating epilepsy and more research is needed.
research Peroxisome Proliferator-Activated Receptors (PPARs) and PPAR Agonists: The Future in Dermatology Therapeutics?
PPAR agonists show promise for skin conditions but need more research before being a main treatment.
research Selective Androgen Receptor Modulators Negatively Regulate Triple-Negative Breast Cancer Growth and Epithelial-Mesenchymal Stem Cell Signaling
SARMs may be an effective treatment for a certain type of breast cancer by blocking cancer growth and spread.
research Hair Follicles, Their Disorders, and Their Opportunities
Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.
research Regulation of VDR by ΔNp63α Is Associated with Inhibition of Cell Invasion
ΔNp63α helps control a protein that stops cancer cells from spreading.
research Acne: Transient Arrest in the Homeostatic Host–Microbiota Dialogue?
Acne is a temporary skin imbalance during puberty that often resolves on its own.
research Are Hair Follicle Stem Cells Promising Candidates for Wound Healing?
Hair follicle stem cells are promising for wound healing but require more research for safe clinical use.
research Platelet-Rich Plasma in the Treatment of Alopecia Areata: A Review
Platelet-Rich Plasma (PRP) could potentially help regrow hair in people with Alopecia Areata, but more research is needed to confirm its effectiveness.
research Suppression of Vitamin D Receptor and Induction of Retinoid X Receptor Alpha Expression During Squamous Differentiation of Cultured Keratinocytes
As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.
research Selective Expansion of Tregs Using the IL-2 Cytokine Antibody Complex Does Not Reverse Established Alopecia Areata in C3H/HeJ Mice
Increasing Treg cells in the skin does not cure hair loss from alopecia areata in mice.
research Discovery of New Drug Therapies Based on the Study of Adverse Reactions
Side effects of drugs can lead to the discovery of new treatments.
research Melanocytes and Vitiligo and Hair Graying
Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.
research From Evidence to Practice: Insights from the Multidisciplinary Team on the Optimal Integration of GLP-1 Receptor Agonists in Obesity Management Services
GLP-1 receptor agonists help with weight loss but need to be combined with other treatments for best results.
research The Role of the Vitamin D Receptor in the Epidermal Stem Cell Response to Wounding
Vitamin D receptor is crucial for skin wound healing.
research The Potential Teeth Bleaching and Halitosis Prevention Effects of Pediococcus Inopinatus THK-30, a Kimchi-Derived Lactic Acid Bacterium: An In Vitro Study
A kimchi-derived bacterium could help whiten teeth and prevent bad breath.
research Natural Bioactive Compounds as Potential Sources for Alleviation and Treatment of Androgenetic Alopecia: A Research Advance
Natural compounds from Chinese herbs may safely promote hair growth and treat common hair loss.
research Downstream Molecular Responses to Volatile Signaling in Roots
Plant roots respond to fungus smells by possibly using certain proteins and a plant hormone to change root growth, but more research is needed.
research Effects of Altering Allopregnanolone Levels During Critical Neurodevelopmental Periods on Alcohol Consumption Vulnerability
Early NAS level changes affect alcohol consumption vulnerability.
research Modulating the Stem Cell Niche for Tissue Regeneration
Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.
research Polymeric Nanoparticles-Based Topical Delivery Systems for the Treatment of Dermatological Diseases
Polymeric nanoparticles show promise for treating skin diseases.
research Androgenetic Alopecia and Microinflammation
Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.
research Cutaneous Reactions to Chemotherapeutic Drugs and Targeted Therapy for Cancer
Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.
research Steroid 5α-Reductase as a Novel Therapeutic Target for Schizophrenia and Other Neuropsychiatric Disorders
S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.
research Hair Follicle: A Novel Source of Multipotent Stem Cells for Tissue Engineering and Regenerative Medicine
Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.