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LGR5 is a marker found in hair follicle stem cells in various species and is important for hair growth and skin repair.

Animal models help study psoriasis but have limitations and don't fully mimic the human disease.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

The hexosamine pathway helps protect skin cells from stress and may improve skin and hair health.

CRISPR/Cas9 editing in spinach affects root hair growth by altering specific genes.

Erythropoietin overexpression disrupts hair growth and fat formation in mice.

Shh and Dhh affect skin development and can cause tumors, while Ihh does not.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Neutrophils quickly move to the site of skin injury.

Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.

Mice with a changed Hr gene lose and regrow hair due to changes in the gene's activity.

Scientists used a special imaging technique to observe that hair follicle regeneration involves cell division and structural changes, mostly in the lower part of the follicle, and that the dermal papilla at the base is crucial for regrowth.

The gene Endothelin 3 makes mice's fur darker by increasing pigment cells and pigment levels.

Blocking a specific protein signal can make hair grow on mouse nipples.

ODC transgenic mice can model human hair loss with skin lesions.

Wnt and Shh signaling are key in noggin-induced tumors, and blocking them can slow tumor growth.

Alopecia areata is influenced by genetics and immune system factors, and better understanding could improve treatments.

Merkel cells stabilize nerve endings in the skin, and they change independently of each other.

Rodent models helped understand psoriasis but none perfectly replicated the disease.

Overexpressing Merkel cell virus proteins in human hair follicles can create clusters of cells that resemble Merkel cell cancer.

Hair grows when stem cell offspring in the follicle base proliferate, influenced by the dermal papilla.

Prostaglandin D2, found in higher levels in bald scalps, stops hair growth, suggesting that blocking its receptor could potentially treat hair loss.

The KRTAP11-1 gene promoter is crucial for specific expression in sheep wool cortex.

Activating the hexosamine pathway can improve skin health and increase hair follicle stem cells.

Scientists made a mouse that can be made to lose hair and then grow it back.

The HPV type 11 region activates hair-specific gene expression in mice.

A genetic change in the EDAR gene causes the unique hair traits found in East Asians.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Testosterone can both promote hair growth and cause baldness by affecting hair growth signals.

Acid inside cells speeds up aging and turns on aging signs in mice.