Live Imaging of Stem Cell and Progeny Behavior in Physiological Hair-Follicle Regeneration
October 2012
in “
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
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hair follicle regeneration stem cells progeny intravital two-photon imaging transgenic mouse green fluorescent protein GFP keratin 14 promoter HF epithelial cells mitotic activities bulge stem cells dermal papilla DP mesenchymal component HF homeostasis two-photon imaging epithelial cells homeostasis
Studysummary Scientists used a special imaging technique to observe that hair follicle regeneration involves cell division and structural changes, mostly in the lower part of the follicle, and that the dermal papilla at the base is crucial for regrowth.
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