Search
for

    Did you mean Transgenic Mouse Model?
    Glossary Transgenic Mouse Model

    A transgenic mouse model is a genetically modified organism that has had a foreign gene inserted into its genome, allowing researchers to study the effects of specific genes on biological processes, including hair loss and hair biology. These models are particularly relevant in the field of hair research as they can mimic human hair loss conditions, such as androgenetic alopecia or alopecia areata, providing insights into the underlying mechanisms and potential therapeutic targets. Key distinguishing characteristics of transgenic mouse models include the ability to control gene expression and the capacity to observe phenotypic changes in hair growth and follicle development in a living organism.

    Related Terms

    Research 10 of 1000+

    1. Directed Expression of Keratin 16 to the Progenitor Basal Cells of Transgenic Mouse Skin Delays Skin Maturation The Journal of Cell Biology · 1998 · 79 citations
    2. Transgenic mouse models support HCR as an effector gene in the PSORS1 locus 2004 · 37 citations
    3. Characterization of a new, inducible transgenic mouse model with GFP expression in melanocytes and their precursors Gene Expression Patterns · 2017 · 14 citations
    4. A transgenic mouse model to study the role of epidermal growth factor (EGF) in hair and skin development 2002
    5. TCL1 transgenic mouse model as a tool for the study of therapeutic targets and microenvironment in human B-cell chronic lymphocytic leukemia Cell Death and Disease · 2016 · 38 citations
    6. Transgenic rescue of desmoglein 3 null mice with desmoglein 1 to develop a syngeneic mouse model for pemphigus vulgaris Journal of Dermatological Science · 2011 · 17 citations
    7. Overexpression of spermidine/spermine N1-acetyltransferase under the control of mouse metallothionein I promoter in transgenic mice: evidence for a striking post-transcriptional regulation of transgene expression by a polyamine analogue Biochemical Journal · 1999 · 13 citations
    8. High‐Sulfur Protein Gene Expression in a Transgenic Mouse Annals of the New York Academy of Sciences · 1991 · 10 citations
    9. c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny Current Biology · 2001 · 338 citations
    10. Overexpression of spermidine/spermine N1-acetyltransferase under the control of mouse metallothionein I promoter in transgenic mice: evidence for a striking post-transcriptional regulation of transgene expression by a polyamine analogue Biochemical Journal · 1999 · 43 citations
    All research results →

    Learn

    — no results

    Try a deeper search in learn →

    Community

    — no results

    Try a deeper search in community →