25 citations
,
January 2015 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
24 citations
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October 2017 in “Biomolecules” Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
23 citations
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May 2019 in “Expert Opinion on Therapeutic Patents” New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.
23 citations
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June 2012 in “PLOS ONE” KLF4 is important for maintaining skin stem cells and helps heal wounds.
21 citations
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November 2022 in “Frontiers in immunology” Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
21 citations
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October 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” A specific gene change plus an additional mutation in the same gene cause hereditary trichilemmal cysts.
21 citations
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November 2017 in “Journal of Investigative Dermatology” The document concludes that understanding dermal papilla cells is key to improving hair regeneration treatments.
20 citations
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September 2021 in “Nature communications” Cat color patterns are determined early in development by gene expression and epidermal changes, with the Dickkopf 4 gene playing a crucial role.
20 citations
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January 2017 in “Scientific reports” Whale genes show changes that help them live in water, like less hair and better flippers.
19 citations
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July 2015 in “Developmental Dynamics” The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
18 citations
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September 2020 in “BMC Public Health” Non-Kuwaiti COVID-19 patients had worse health outcomes than Kuwaitis, likely due to poorer socioeconomic conditions.
18 citations
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January 2020 in “Ecology and evolution” Genes related to pigmentation, body rhythms, and behavior change during hares' seasonal coat color transition, with a common genetic mechanism in two hare species.
18 citations
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February 2019 in “Scientific Reports” Trichostatin A helps restore hair-growing ability in skin cells used for hair regeneration.
18 citations
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December 2009 in “Canadian Journal of Animal Science” The BMP2 gene is more active in the early growth phase of Cashmere goat hair and may affect hair regeneration and textile production.
17 citations
,
May 2019 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.
14 citations
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February 2020 in “Stem Cells International” Umbilical cord cells safely improve healing in long-term nonhealing wounds better than a placebo.
14 citations
,
February 2016 in “Experimental and molecular pathology” Giving immune serum from vaccinated mice to mice without T cells prevents infection and tumor growth.
13 citations
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April 2022 in “Frontiers in oncology” Melanoma development can be linked to the breakdown of skin's melanin-producing units.
13 citations
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January 2020 in “Scientific Reports” The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.
13 citations
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February 2015 in “Stem Cells” Hair and skin can regenerate without bulge stem cells due to other compensating cells.
13 citations
,
April 2013 in “Applied and Environmental Microbiology” A gene in Sebekia benihana, CYP-sb21, is needed for a specific reaction on the drug Cyclosporine A, which could be important for hair growth without affecting the immune system.
12 citations
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February 2021 in “Translational Psychiatry” Researchers found two new genetic variants linked to Alzheimer's disease.
12 citations
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December 2014 in “Journal of Investigative Dermatology” Chemotherapy causes complex changes in hair follicle cells that can lead to hair loss.
11 citations
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June 2022 in “Frontiers in immunology” New protein changes may be involved in the immune attack on hair follicles in alopecia areata.
11 citations
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December 2018 in “Bone” Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.
11 citations
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January 2016 in “Journal of Functional Foods” Hibiscus petals improved blood sugar and stress responses in diabetic rats.
11 citations
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June 2013 in “Journal of Proteomics” Found different proteins in balding and non-balding cells, giving insight into hair loss causes.
10 citations
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December 2021 in “Frontiers in cell and developmental biology” Glypican-1 is important for blood vessel growth in hair follicles and could help treat hair loss.
10 citations
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April 2013 in “Stem Cells and Development” Scientists identified a unique type of human skin stem cell that could help with tissue repair.
8 citations
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August 2020 in “PLOS Computational Biology” A machine learning model called CATNIP can predict new uses for existing drugs, like using antidepressants for Parkinson's disease and a thyroid cancer drug for diabetes.