5 citations
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May 2024 in “BMC Genomics” This study analyzed the transcriptome of the Tianzhu white yak, identifying differential transcripts that shed light on the molecular mechanisms influencing hair length growth variation in this species.
May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study reported the first comprehensive transcriptome atlas of the extraorbital lacrimal gland in mice, identifying over 41 cell subclasses and revealing significant cell-cell communication networks, particularly among innate lymphoid cells.
March 2024 in “International journal of molecular sciences” In this study on Angora rabbits, researchers identified genetic factors influencing wool fiber diameter by analyzing hair follicle proteins, highlighting keratin family members and other proteins as key contributors to fiber differences between coarse and fine wool.
April 2018 in “Journal of Investigative Dermatology” This study used single-cell RNA sequencing to identify at least nine subpopulations of keratinocytes in human neonatal epidermis, revealing unexpected heterogeneity and complex differentiation trajectories.
April 2019 in “Journal of Investigative Dermatology” This study reported that mSKPs and DMSCs share similarities in biological characteristics but exhibit distinct transcriptome profiles, with mSKPs being more immune-related and DMSCs more associated with differentiation and disease pathways.
72 citations
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August 2014 in “Genome Biology and Evolution” This study found that the differential expression of α- and β-keratin genes in feathers may explain their morphological and structural diversity, highlighting the chicken as a model for studying keratin-related diseases.
11 citations
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October 2023 in “mSphere” This study reported that the PrrH sRNA in *Pseudomonas aeruginosa* may directly regulate genes involved in pyochelin siderophore biosynthesis, highlighting its role in adapting to heme availability, with light conditions influencing this gene expression.
April 2024 in “Pigment cell & melanoma research” This study explored the diversity of melanocyte stem cell subpopulations in the hair follicles of adult female mice and identified novel groups with distinct immune privilege regulation, suggesting a heterogeneous landscape that future research should consider.
4 citations
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July 2025 in “Frontiers in Immunology” This study explored peripheral blood immune dysregulation in alopecia areata through single-cell analyses, identifying systemic changes linked to disease severity and key signaling roles for monocytes, NK cells, and memory T cells, suggesting potential therapeutic targets.
4 citations
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January 2020 in “Cells” This study found that the transcriptome of skin stem cells in mice changes significantly with age, revealing specific age-dependent biological programs and transcriptional hubs.
November 2025 in “Frontiers in Veterinary Science” In this study, feeding H-line chickens a diet with 1.0% tyrosine for 40 days significantly increased melanin deposition in feathers and revealed changes in gene expression related to melanin pathways, suggesting tyrosine's involvement in regulating feather color through the EDNRB2 regulatory network.
127 citations
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March 2016 in “PLoS ONE” This study found that transcriptome profiling of cashmere goat skin revealed key genes and pathways involved in hair follicle initiation, differentiation, and maturation, which are critical for improving fleece production.
19 citations
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June 2020 in “Animals” This study found that maternal sub-maintenance nutrition reduced the density and branching ratio of secondary wool follicles in Merino sheep fetuses and identified genes potentially involved in these processes.
14 citations
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January 2015 in “Genetics and molecular research” This study found that numerous genes involved in hair growth, including 73 co-up-regulated ones, were differentially expressed in goat hair follicles during the hair growth cycle.
May 2025 in “Journal of Food and Nutrition Research” In this study, black wolfberry ferment was found to promote hair regrowth in mice with androgenetic alopecia by increasing hair weight, follicle count, and skin thickness, potentially through PI3K/AKT, NF-kappa B, and MAPK signaling pathways.
10 citations
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December 2019 in “in Vivo” This study found that administering testosterone to ovariectomized female rats decreased endometrial tight junction complexity and expression of specific proteins, potentially affecting embryo implantation.
February 2024 in “Biomedical materials” This study developed a new human in vitro hair model that replicates in vivo hair characteristics and may be suitable for high throughput screening of hair growth treatments.
August 2025 in “Dermatology and Therapy” This study conducted a meta-analysis of gene expression data from alopecia areata patients, identifying 5109 differentially expressed genes and highlighting enriched pathways like JAK-STAT signaling, providing insights into the disease's pathogenesis and potential treatment targets.
112 citations
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September 2021 in “BMC Biology” This study found that specific gene expressions during different stages of hair follicle development in Merino sheep are linked to wool-related traits, and may also be relevant to human skin, metabolic, and immune traits.
5 citations
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September 2021 in “Frontiers in Cell and Developmental Biology” This study found that 3D-cultured dermal papilla cells more accurately mimic in vivo conditions compared to 2D cultures, enhancing our understanding of molecular mechanisms in androgen-induced alopecia.
61 citations
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December 2016 in “The EMBO Journal” This study established a new in vitro culture system that supports the growth and dynamic self-organization of hair follicle stem cells and their progeny, promoting a stable population equilibrium.
45 citations
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October 2015 in “BMC Genomics” This study identified morphotype-specific gene expression patterns in feathers, enhancing understanding of the molecular and cellular processes involved in feather development and diversification.
59 citations
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February 2019 in “BMC Genomics” In this study, transcriptome analysis suggested that lipid metabolism and apoptosis may be key factors influencing hair length differences between short-hair and long-hair rabbits.
55 citations
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August 2013 in “PloS one” This study suggests that changes in expressed transcripts and splice isoforms may explain the transition from curly to straight fleece in Chinese Tan sheep as they age.
21 citations
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January 2018 in “Journal of Investigative Dermatology” This study found that large excisional wounds in rats across seven strains do not regenerate new hair follicles, unlike in mice, possibly due to differences in epidermal competence and transcriptional profiles.
3 citations
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July 2023 in “Frontiers in Aging” This research detailed a single-cell atlas showing dynamic hair follicle stem cell states associated with the hair cycle during aging in mice, highlighting differences in chromatin landscape linked to stem cell differentiation and quiescence, and providing a foundation for future exploration of aging reversal.
2 citations
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July 2023 in “Animals” In this study, researchers investigated a regulatory network in cashmere goat embryos and found that fibroblast growth factor 10, alongside non-coding RNAs, significantly influences hair follicle cell proliferation, offering insights into the biology of hair follicles in cashmere goats.
1 citations
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October 2025 in “Scientific Reports” This study investigated the Mandarin duck as a model for understanding lifelong developmental changes, finding that male sail feather morphogenesis involves a combination of local morphogenetic programs, epigenetic regulation, and hormonal cues, with increased female estrogen levels observed before the mating season.
May 2026 in “JID Innovations” This study found a significant overlap between gene expression signatures of alopecia areata and certain chronic inflammatory skin disorders, suggesting shared biological processes may drive their co-occurrence and providing a foundation for future research into distinct comorbid subtypes.
January 2026 in “Veterinary Sciences” In this study, researchers found that significant transcriptomic changes occur in the skin of Dezhou donkey foals as they age from newborns to one year old, involving gene expression shifts that may enhance skin barrier function and hair follicle development, while reducing collagen synthesis.