39 citations,
March 2018 in “Archives of Dermatological Research” Androgens may block hair growth signals, targeting this could treat hair loss.
10 citations,
October 2021 in “Animal nutrition” Vitamin B6 helps increase hair growth and density in rabbits by affecting certain cell signaling pathways.
69 citations,
April 2019 in “Biomedicines” PRP and HF-MSCs treatment improves hair growth, thickness, and density in androgenetic alopecia.
53 citations,
April 2021 in “Cell Host & Microbe” Skin bacteria, specifically Staphylococcus aureus, help in wound healing and hair growth by using IL-1β signaling. Using antibiotics on skin wounds can slow down this natural healing process.
40 citations,
August 2022 in “Frontiers in immunology” Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.
January 2018 in “Stem cell biology and regenerative medicine” The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
271 citations,
March 1999 in “Developmental biology” The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.
74 citations,
June 2013 in “Journal of Investigative Dermatology” Four genetic risk spots found for hair loss, with WNT signaling involved and a link to curly hair.
48 citations,
July 2008 in “Acta Biochimica et Biophysica Sinica” Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.
22 citations,
August 2006 in “Critical Reviews in Plant Sciences” The tropical legume Sesbania rostrata can form nodules in waterlogged conditions using a different method that involves plant hormones and specific genes.
182 citations,
November 2017 in “Molecular Aspects of Medicine” The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.
42 citations,
October 2011 in “Seminars in Cell & Developmental Biology” Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
144 citations,
November 2020 in “Frontiers in immunology” Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.
41 citations,
October 2008 in “The American journal of pathology” Blocking a specific protein signal can make hair grow on mouse nipples.
28 citations,
October 2011 in “International Journal of Molecular Medicine” Adenosine helps hair grow longer and stronger by boosting certain growth factors and signaling pathways.
9 citations,
July 2001 in “Cell” Cells from certain embryo parts can induce head formation in another embryo, involving complex signaling pathways.
January 2023 in “Biocell” Safflower extract helps protect hair follicle cells from damage caused by chemotherapy.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Most patients experienced mild to moderate skin problems during a trial for a desmoid tumor treatment.
November 2017 in “British Journal of Dermatology” Genes controlling hair growth and immune response are disrupted in male pattern baldness.
Editing the FGF5 gene in sheep increases fine wool growth.
89 citations,
September 2010 in “Annual Review of Genomics and Human Genetics” The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.
71 citations,
November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Edar signaling is crucial for proper hair follicle development and function.
49 citations,
November 2014 in “Journal of Medicinal Food” Red Ginseng Extract may help human hair grow by activating growth pathways and blocking negative effects of certain hormones.
43 citations,
August 2018 in “Cell Stem Cell” Hoxc genes control hair growth through Wnt signaling.
18 citations,
January 2017 in “PloS one” Certain genes and pathways are crucial for high-quality brush hair in Yangtze River Delta White Goats.
17 citations,
June 2017 in “British Journal of Dermatology” The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.
14 citations,
March 2019 in “Journal of Cosmetic Dermatology” Activated platelet-rich plasma helps hair growth by boosting growth factors and cell growth pathways in hair cells.
6 citations,
September 2019 in “Archives of Dermatological Research” Found 32 genes linked to male baldness, affecting hair growth and stress-related pathways.
4 citations,
November 2017 in “Scientific Reports” The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.
October 2021 in “Research Square (Research Square)” Melatonin affects certain genes and pathways involved in cashmere goat hair growth.