12 citations
,
January 2016 in “Skin appendage disorders” This study reports that women receiving periodic injections of botulinum toxin type A for forehead wrinkles may experience frontal alopecia, with progressive hairline recession observed in the cases studied.
12 citations
,
August 2015 in “Plastic Surgery” This study found that botulinum toxin type A significantly reduced skin flap necrosis in rats exposed to cigarette smoke, suggesting it may help improve flap viability in smokers.
12 citations
,
May 2015 in “Journal of the National Comprehensive Cancer Network” This article provides a narrative on managing dermatologic side effects from cancer therapies and suggests strategies that oncologists could adopt, but it reports no new clinical findings.
10 citations
,
May 1978 in “Acta Dermato Venereologica” In this study, seven patients with generalized toxic erythema developed sterile pustules localized to hair follicles or sweat ducts, with most having a history of medication, solvent exposure, or infection.
10 citations
,
January 2020 in “Biomedicine & Pharmacotherapy” This study found that XiaoZhenFang (XZF) reduced skin toxicities caused by Erlotinib in a mouse model, likely through mechanisms involving inflammation and EGFR-related pathways.
10 citations
,
October 2014 in “Plastic & Reconstructive Surgery Global Open” In this case study, Botulinum toxin type A injections were associated with improved hair growth and scalp condition in a patient with radiation-induced alopecia, though the mechanisms remain speculative.
9 citations
,
January 2023 in “Cellular and Molecular Life Sciences” This study found that intrauterine administration of botulinum toxin A improved endometrial environment and receptivity in a murine model of thin endometrium through mechanisms involving IGFBP3 and osteopontin.
9 citations
,
June 2013 in “Journal of Cosmetic Dermatology” The study suggests that lateral oblique forehead lines result from muscle contractions and can be effectively treated with onabotulinum toxin A, rather than being caused by sleeping position.
8 citations
,
March 2022 in “Dermatologic Therapy” This article provides information on data availability but reports no new research findings.
8 citations
,
October 2017 in “Dermatologic Surgery” This review discusses male-specific techniques for botulinum toxin application to enhance aesthetic treatment outcomes in men and reports no new clinical results.
7 citations
,
April 2021 in “Journal of advanced pharmaceutical technology & research” This study reported that compound 16 (olean-12-en-3beta-ol, cinnamate) from Merremia peltata showed potential as an androgen receptor antagonist, suggesting it may benefit alopecia treatment based on molecular docking and ADME-Tox predictions.
7 citations
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April 2025 in “Journal of the American Academy of Dermatology” This scoping review investigates cases of toxic minoxidil exposure in cats and dogs, detailing their clinical presentations, management strategies, and outcomes, without reporting specific results.
7 citations
,
March 2022 in “Scientific reports” In this study, researchers found that pigs with genetically disrupted ANTXR1 were resistant to Senecavirus A infection, showing no clinical symptoms, and provided a model for human GAPO syndrome, while confirming ANTXR1 as a receptor for the virus.
7 citations
,
October 2003 in “Nonlinearity in Biology Toxicology Medicine” This review discusses attempts to confirm low-dose effects in rodent endocrine studies and reports no findings; variability in control groups hinders demonstrating weak effects.
6 citations
,
May 2016 in “British Journal of Dermatology” This study reports the effective use of botulinum toxin A in treating multiple facial apocrine hidrocystomas in a 29-year-old man, a case not previously documented in English-language literature.
6 citations
,
December 2014 in “PubMed” This report describes three cases of liver toxicity linked to the dietary supplement Inneov masa capilar®, primarily composed of green tea catechins, after ruling out other causes of acute hepatitis.
5 citations
,
January 2018 in “Javma-journal of The American Veterinary Medical Association” This case report documents the first successful management of accidental minoxidil toxicosis in a dog, resulting in full recovery after treatment with supportive care, including medications for blood pressure and potential toxicity mitigation.
5 citations
,
May 2022 in “Molecules” This article reviews the literature on the off-label use of botulinum toxin for dermatological conditions, highlighting its potential effectiveness in treating rosacea, anal fissures, Raynaud phenomenon, hypertrophic scars, keloids, and hidradenitis suppurativa.
5 citations
,
February 2019 in “Journal of oceanology and limnology (Online)” This study found that adding 7% Ecklonia cava extract to oxidative hair dyes significantly reduced their cytotoxicity and oxidative stress without affecting color performance.
5 citations
,
April 2014 in “Journal of Lipid Research” This study demonstrates a method to noninvasively assess lipid classes in rodent sebum via high-field proton NMR, observing significant lipid reductions in rats treated with an SCD1 inhibitor.
5 citations
,
January 2000 in “Inhalation Toxicology” This study found that exposure to aqueous dispersion resin in aerosol form increased lung weights and caused histopathological changes in animals at higher concentrations, with a no-observable-effect level at 30 mg/m³.
4 citations
,
March 2002 in “International journal of toxicology” In this study on tolerant rats, maternal and developmental toxicity from levo-alpha-acetyhnethadol hydrochloride were observed at all doses, without specific fetal toxicity or teratogenic effects.
4 citations
,
August 2022 in “Aesthetic Surgery Journal” This study found that one session of intradermal botulinum toxin type A injection decreased scalp sebum secretion and perception of greasiness more effectively than saline for up to 3 months.
4 citations
,
April 2021 in “Journal of Cosmetic Dermatology” Botulinum toxin may help hair loss by increasing blood flow and reducing harmful factors.
4 citations
,
January 2021 in “PubMed” This review discusses the pathogenesis and management of hidradenitis suppurativa, examining conventional treatments and exploring botulinum toxin type A as a potential therapeutic option, but it reports no new clinical results.
4 citations
,
March 2012 in “Annals of oncology” In this study, a combined therapy of nicotinamide and green tea polyphenols was reported to improve EGFR inhibitor-related skin toxicity and patient quality of life, suggesting it merits further investigation.
3 citations
,
November 2024 in “Pediatric Dermatology” This study found that dermatologic adverse events are common in children taking MEK inhibitors, with selumetinib patients experiencing less severe reactions and a lower risk of dosage adjustments. Age was noted as a factor in the likelihood of specific skin reactions.
3 citations
,
October 2024 in “Cancers” In this study, 37.5% of patients with nodal or metastatic cutaneous melanoma treated with immune checkpoint inhibitors developed skin adverse events, primarily low-grade rashes, vitiligo, and other dermatological symptoms, occurring mainly after 10 weeks of treatment.
3 citations
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January 2022 in “Journal of Cosmetic Dermatology” This study found that for treating androgenetic alopecia, LC hair essence serum injections provided excellent results with fewer side effects compared to botulinum toxin A, which also showed significant efficacy but with higher associated costs and more frequent side effects.
3 citations
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January 2022 in “Neurotoxicity Research” This study found that botulinum toxin type A injections in stressed mice appeared to normalize hair follicle regeneration cycles and reduced stress-related hair loss indicators.