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The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Sebocytes play a key role in controlling androgen levels in human skin.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Male pattern baldness involves genetics, hormones, and needs better treatments.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

Humans lost body hair relatively recently in evolution.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.

Taking 1 mg/day finasteride for hair loss significantly lowers PSA levels in men, which may affect prostate cancer screening.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Targeting the skin's endocannabinoid system could help treat skin disorders.

TRH stimulates human hair growth and extends the hair growth phase.

Human hair follicles produce and respond to erythropoietin, helping protect against stress.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.