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DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.

The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.

Eating a balanced diet with the right vitamins and minerals is important for healthy hair, but too many supplements can be harmful.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Current treatments for male pattern baldness include minoxidil and finasteride, with new options being developed.

Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

New drugs for heart disease may be developed from molecules secreted by stem cells.

Alopecia areata, a type of hair loss, is likely an autoimmune disease with a genetic link, but its exact cause is still unknown.

MRI can effectively image skin structures noninvasively.

The document says that treating the root cause of hair follicle damage is crucial to prevent permanent hair loss, and treatment options vary.

Hair follicle regeneration may slow tumor growth.

Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

Pannexin 3 helps skin and hair growth by controlling a protein called Epiprofin.

Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.

DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.

Nanotechnology is improving drug delivery and targeting, with promising applications in cancer treatment, gene therapy, and cosmetics, but challenges remain in ensuring precise delivery and safety.

Hair loss can indicate or worsen with systemic diseases, and treating the underlying condition is important.