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This study found that chitosan nanofibrillar scaffolds accelerated skin wound healing in mice by enhancing cell adhesion, proliferation, and regeneration of epidermis and dermis compared to other forms.

This study observed that keratose, derived from human hair, integrated well in mouse tissue and remodeled with collagen, suggesting potential as a non-toxic biomaterial for regenerative applications.

This study characterized keratin-based biomaterials that self-assemble into hydrogels, demonstrating their potential to achieve hemostasis in a lethal liver injury model through specific biomaterial-receptor interactions.

Human hair keratin can be used in many medical applications.

This study describes a method to create keratin hydrogels with adjustable erosion rates by mixing different ratios of keratose and kerateine, enabling controlled release of therapeutic agents like insulin-like growth factor 1.

In this study, researchers developed a method to differentiate human iPSCs into cells that can generate all lineages of hair follicles, potentially aiding treatments for hair loss and skin disorders.

This study observed that keratose hydrogels sustained ciprofloxacin release over three weeks and inhibited Staphylococcus aureus growth in vitro for 23 days and in mice for 2 weeks.

This review discusses the growing importance of hydrogel scaffolds in skin wound healing, highlighting their unique properties and recent advancements in their use for treating difficult tissue damage, particularly within tissue engineering.

This study found that human hair follicle-derived mesenchymal stem cells can differentiate into myogenic, osteogenic, adipogenic, and chondrogenic lineages, although this potential decreases over time and varies by lineage.

This review discusses the advancements and challenges in developing in vitro human skin models incorporating components like vasculature for drug testing and disease research, but reports no new clinical results.

This study found that applying both dehydrothermal treatment and carbodiimide crosslinking improved the mechanical properties of porcine acellular dermal matrix scaffolds without added cytotoxicity, suggesting potential applications in tissue engineering.

This review highlights recent advances in understanding how the extracellular matrix regulates epidermal stem cell fate, emphasizing the importance of the hair follicle stem cell niche, but reports no new empirical findings.

Burn reconstruction improves with new techniques, materials, and tissue engineering.

This review discusses recent advances in scarless wound healing research, focusing on the roles of mechanobiology and immunology, and reports no new clinical results; the authors highlight the potential of next-generation human skin equivalents in understanding these mechanisms.

This review discusses the potential applications and challenges of small molecules in regenerative medicine, but it reports no new research findings.

This review discusses the use of human mesenchymal stem cells (hMSCs) for treating skin diseases and suggests they show promise for improving conditions like wounds and scleroderma, but more research is needed due to varied study designs and endpoints.

This review discusses the role of pharmacological sciences in advancing regenerative medicine technologies but reports no new experimental findings; the authors advocate for increased pharmacologist involvement to drive innovations.

This article reviews the generation of complex integument patterns through genetic, chemical, and environmental influences, with applications in tissue engineering, but reports no new experimental results.

This study observed that increasing the γ-kerateine content in meta-kerateine materials led to reduced elasticity, solidity, and hydrolytic stability, and decreased hepatocyte attachment support.

This article discusses stem cell-based therapies for wound healing and highlights their potential for tissue repair and regeneration, without presenting new clinical results.

This review discusses advances and challenges in skin tissue engineering, focusing on developing 3D constructs for functional skin substitutes, and reports no new clinical results.

This study found that the DexIEME hydrogel promotes complete skin regeneration and scar attenuation in murine and porcine models, suggesting potential for treating deep dermal injuries.

This review discusses recent research and applications of RADA16 and RADA16-based peptide scaffolds in biomedicine, including their roles in tissue repair and drug delivery, but reports no new clinical results.

This report reviews current advances in hair follicle regeneration for tissue-engineered skin grafts and highlights the feasibility and challenges of creating human hair follicles in this setting, suggesting key bioengineering requirements.

In this study, the RADA-PRG hydrogel enhanced SKP proliferation, survival, and gene expression, effectively supporting hair follicle regeneration in mice.

This article discusses a wide range of procedures in facial plastic surgery and highlights the recent advancements and trends without reporting new clinical findings.

In this study, mouse amnion epithelium was successfully transformed into skin and hair follicles when associated with hair-forming dermis, revealing the necessity of specific influences for follicle formation.

This review discusses the historical development and current challenges in in vitro hair follicle culture, highlighting a need for advanced models using cell lines and tissue engineering, and reports no new results.

The study suggests that a 3D culture system using the RAD16-I peptide scaffold can help restore the original phenotype of hair follicle dermal papilla cells and support their osteogenic and adipogenic differentiation.

This review discusses the applications and potential of Bioengineered Artificial Skin Substitutes in cosmetics and pharmacology research, with no new clinical findings reported.