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Both Th1 and Th2 immune responses are increased in alopecia areata, with Th2 response more strongly linked to how severe the disease is.

Finasteride effectively treats BPH, but needs more trials to understand potential.

Finasteride may reduce prostate bleeding by lowering blood vessel growth factor levels and blood vessel density in certain prostate areas.

DA-9401 helps protect rat testis from finasteride damage.

Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.

Combination therapy for 9+ months maintains symptom improvements after stopping alpha-blockers or finasteride.

HPH-15, a new compound, effectively reduces skin fibrosis in experiments without causing harm.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

Apoptosis is crucial for healthy skin and treating skin diseases.

Finasteride helps reduce heart issues and improves heart function.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Extramammary Paget disease can spread deeply into tissues, reaching up to 3.6 mm.

Researchers developed a mouse model that successfully mimics the bladder damage seen in humans after radiation therapy.

Acne inversa is an epithelial-driven disease where inflammation is caused by cyst rupture, and treatments should focus on preventing tendril growth for better results.

Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Hair follicle regeneration may slow tumor growth.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.

Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.

Ketoconazole increases finasteride's effectiveness and lifespan in the body.

Melatonin stimulates the skin components of ram's scrotum during their non-breeding season.

The document concludes that the hCG protocol may help in obesity treatment and could be scientifically justified, but more research is needed.

Lipedematous alopecia involves a thickened scalp and hair loss, with limited effective treatments available.

T-cell reconstitution after thymus transplantation can cause hair whitening and loss.

New treatments for long-lasting erections improve outcomes but must be timely to avoid lasting damage.

Deleting the Trf1 protein in mice is safe and may help prevent cancer without major side effects.