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This study found that PLDζ2 and NPC4 enzymes play distinct roles in lipid remodeling and root hair growth in Arabidopsis under phosphate deficiency, influencing root hair density and length in a tissue- and time-specific manner.

The study found that different criteria led to different patient groups in the CombAT study compared to the MTOPS study.

In this study, the safety profile of the prodrug CAP7.1 was found to be similar to other topoisomerase inhibitors, with myelosuppression as the main dose-limiting toxicity.

This study found that trans-3,4'-Dimethyl-3-hydroxyflavanone reduces active TGF-beta2 levels in human keratinocytes, suggesting it may enhance hair growth by suppressing the TGF-beta2 activation pathway.

This case report describes trichothiodystrophy in two sisters with only hair fragility, illustrating the condition's variable presentation and the importance of regular monitoring for potential associated impairments.

This study aimed to evaluate the outcomes of switching between two JAK inhibitors, tofacitinib and baricitinib, in treating alopecia areata, due to the lack of data on their comparative efficacy.

Complex basal cell carcinomas need personalized treatment due to unique genetic mutations.

In this study, a daily topical application of a 0.05% tretinoin solution effectively removed dark plugs and resolved symptoms of trichostasis spinulosa.

In this study, minoxidil 2% solution was more effective than tacrolimus 0.1% ointment for promoting hair regrowth in mild to moderate patchy alopecia areata.

This study reports that daily topical application of a 0.05% tretinoin solution can eliminate the hair plugs and symptoms associated with trichostasis spinulosa.

This case report details a rare instance of malignant proliferating trichilemmal tumour in a 60-year-old male, emphasizing the significance of histochemical and immunohistochemical markers for accurate diagnosis and differentiation from squamous cell carcinoma.

Ritlecitinib may help treat alopecia areata by protecting hair follicles.

This study found that activating the erbB-2 oncogene in transgenic mice led to severe skin abnormalities and fatal defects, indicating erbB-2's significant role in skin and hair follicle development.

Temporal triangular alopecia is a lifelong condition with hairless patches on the side of the head that may be present from birth.

Terbinafine can cause hair loss.

This study found that the absence of the stress-responsive protein Sesn2 increased hair cell susceptibility to gentamicin in the inner ear, indicating Sesn2's potential protective role against aminoglycoside-induced damage.

In this study, PKCepsilon transgenic mice showed increased TNFalpha shedding during skin tumor promotion, which may contribute to the development of metastatic squamous cell carcinoma.

This study found that overexpression of the transcription factor Tcf3 accelerates keratinocyte migration and skin wound healing in mice, highlighting its potential as a therapeutic target for wound repair.

This study found that mesenchymal progenitor cells from human hair roots seeded onto polymer scaffolds stimulated the production of mineralized proteins, enhancing bone-like structures, with optimal results at a pore size of 35 µm.

Sirolimus can reduce tumor cell size in TSC-related skin tumors, but continuous treatment is needed to maintain benefits.

This study observed that Trps1 gene expression in mice is precisely regulated in skin development, particularly during hair follicle morphogenesis, with distinct localization patterns in different cell types.

This study found that Ang1 improved survival and proliferation in human follicle dermal papilla cells under DHT-induced stress, suggesting potential as a therapeutic candidate for androgenetic alopecia.

This study found that HtrA2 inactivation in mnd2 mice is associated with delayed hair cycle phases and growth retardation of adipocytes, suggesting HtrA2's role in regulating adipogenesis-related hair growth.

Early-stage skin substitutes improve wound healing and skin structure.

This study provided the crystal structure of the human steroid 5α-reductase 2 enzyme and identified key molecular mechanisms for testosterone reduction and finasteride inhibition, aiding in understanding disease-causing mutations and potentially facilitating new drug development.

This study found that the Arabidopsis cation chloride cotransporter (CCC1) is crucial for regulating pH and processes in the trans-Golgi-network/early endosome, impacting plant growth and stress responses.

This study found that ALRN-6924, a clinical-stage dual inhibitor, can selectively protect human scalp hair follicles from paclitaxel-induced toxicity and damage by inducing transient cell cycle arrest in healthy cells without affecting cancer cells, potentially reducing chemotherapy-induced alopecia.

This study found that three protocols for generating Titan cells in vitro from Candida neoformans vary in their kinetics and transcriptomic profiles, pointing to differences which could impact further research.