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This study presents a new mouse model for investigating chronic graft-versus-host disease, highlighting the role of human thymic tissue in developing multiorgan fibrosis driven by human immune cells.

This study found that VDAC2 promotes apoptosis in secondary hair follicle stem cells of Albas cashmere goats by activating the P53 signaling pathway, with knockdown of VDAC2 reducing apoptosis and a P53 inhibitor partially rescuing VDAC2-induced apoptosis.

This study suggests that common proteomic changes, including the expression of the protein S100A6, may occur during the expansion of AD-MSC from different donors.

This study demonstrates that canonical Wnt signaling is crucial for maintaining thymic epithelial microenvironments in postnatal thymus, possibly by affecting TEC progenitor cells.

This study found that mesenchymal cells from different organs exhibit substantial heterogeneity, with thymic mesenchymal cells particularly adapted for interacting with epithelial and hematolymphoid cells in high-apoptosis environments.

New findings suggest targeting IL-23 could treat psoriasis, skin cells can adapt to new roles, direct conversion of skin cells to blood cells may aid cell therapy, removing certain tumor cells could boost cancer immunotherapy, and melanoma may have many tumorigenic cells, not just cancer stem cells.

This review summarizes how genetic studies using conditional β-catenin loss- and gain-of-function mice have advanced understanding of canonical Wnt signaling's role in embryonic development, adult stem cell maintenance, and cancer modeling.

This review discusses Omenn syndrome, a form of severe combined immunodeficiency, highlighting its immunopathology and genetic defects without presenting new clinical results.

This review highlights the role of matriptase in epithelial differentiation and cancer, noting that unregulated matriptase expression can enhance cancer progression in animal models, but reports no new experimental data.

This study found that deleting the miRNA processing enzymes Drosha and Dicer from mouse skin epithelial cells disrupted normal hair follicle development and maintenance, leading to follicular degradation and stem cell loss during the growth phase.

This review discusses the potential of ultraviolet (UV) radiation technologies in wound care, highlighting their antimicrobial properties and risks of DNA damage, but reports no new clinical findings.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

This review discusses the potential of single cell technologies to improve understanding and treatment of impaired wound healing and reports no new clinical results.

This review discusses the human Nude/SCID phenotype and FOXN1 gene's role in immunological disorders affecting T-cell development but reports no new clinical findings.

In this study, over-expression of FoxN1 in early life was associated with detrimental effects on thymic and skin epithelial development in mice.

TAT-GILZ peptide promotes hair growth by boosting stem cell activity.

This review examines the role of Sonic Hedgehog signaling in the maintenance and repair of skin and lung barriers, and its influence on inflammation and atopic diseases; it presents no new clinical findings.

This paper discusses the balance between target tissue destruction and recovery rates in autoimmune diseases, proposing that high recovery rates are crucial for remitting-relapsing patterns, while exercise might not be neuroprotective in secondary progressive multiple sclerosis.

This study found that CTIP2 is highly expressed in mouse skin during embryogenesis and adulthood, suggesting it may play a role in skin development and homeostasis.

This review summarizes existing knowledge on the role of FOXN1 as a key regulator of thymic epithelial cell lineage and function, reporting no new experimental results.

This study found that over- and ectopic-expression of FoxN1 in early life negatively affected the development of thymic epithelial cells, T and B cells, and skin epithelial cells.

This review discusses the roles and mechanisms of chromatin remodelers and their subunits in mammalian development, but reports no new experimental results.

In this study, the disruption of Gh/tissue transglutaminase in mice did not affect viability but reduced thymocyte viability and fibroblast adhesion, suggesting its role in cell stabilization and extracellular matrix interactions.

This review focuses on S100A6, a Ca²⁺-binding protein, detailing its role in cell functions, the regulation of its expression, and its potential as a biomarker and therapeutic target in various diseases.

This review provides an in-depth analysis of the structure and function of c-kit activation, and its role in both normal physiological and pathological conditions, with no new research findings reported.

This study found that stimulating toll-like receptor 5 via mucosal delivery of a flagellin-containing fusion protein effectively extended lifespan and enhanced healthspan in mice, including improved bone density and cognitive capacity.

This study found that the zinc transporter ZIP10 is crucial for epidermal development, as it influences the activity of p63, promoting epidermal morphogenesis.

This review discusses regenerative medicine and explores the potential of molecular imaging in enhancing personalized therapies, but it reports no new research results.

This study found that CRABP1, Nestin, and Ephrin B2 are expressed in both the tumor stroma and invasive front of skin adnexal tumors and basal cell carcinomas.

In this study, basal cell carcinoma developed in Ptch-deficient mice only after chemical treatment, not skin wounding, suggesting a second unknown event is necessary for tumor formation.