research Treatment of Hypothyroidism with Intrathyroidal Injection of Autologous PRP
Injecting patients' own PRP into their thyroid improved thyroid function and symptoms in most hypothyroidism cases.
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research Deletion of the Developmentally Essential Gene ATR in Adult Mice Leads to Age-Related Phenotypes and Stem Cell Loss
Removing the ATR gene in adult mice causes rapid aging and stem cell loss.
research Permanent Chemotherapy-Induced Nonscarring Alopecia and Premature Ovarian Failure
Chemotherapy caused a woman's permanent hair loss and early menopause.
research Dermal Niche Signaling and Epidermal Stem Cells
Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
research Thymosin Beta 4 Increases Hair Growth by Activation of Hair Follicle Stem Cells
Thymosin β4 promotes hair growth by activating stem cells in hair follicles.
research Modulating the Stem Cell Niche for Tissue Regeneration
Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.
research Epigenetic Control of Adult Stem Cell Function
Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.
research Fresh Umbilical Cord Blood as a Source of Multipotent Stem Cells: Collection, Banking, Cryopreservation, and Ethical Concerns
Umbilical cord blood is a valuable source of stem cells for medical treatments, but its use is less common than other transplants, and there are ethical issues to consider.
research Function of KLF4 in Stem Cell Biology
KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.
research Foxp1 Regulates the Proliferation of Hair Follicle Stem Cells in Response to Oxidative Stress During Hair Cycling
Foxp1 helps control hair stem cell growth and response to stress during hair growth cycles.
research Treatment of Full-Thickness Skin Wounds with Blood-Derived CD34+ Precursor Cells Enhances Healing with Hair Follicle Regeneration
Blood-derived CD34+ cells speed up healing, reduce scarring, and regrow hair in skin wounds.
research A New Horizon in Facial Plastic Surgery: Skin Tissue Engineering and Stem Cell Therapy—Reality or Dream?
Stem cells could potentially rebuild missing structures in wounds, improving facial skin replacement techniques.
research Temporal Layering of Signaling Effectors Drives Chromatin Remodeling During Hair Follicle Stem Cell Lineage Progression
Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.
research Thymic Mesenchymal Cells Have a Distinct Transcriptomic Profile
Thymic mesenchymal cells have unique gene expression that supports their specific functions in the thymus.
research Ultraviolet Radiation in Wound Care: Sterilization and Stimulation
UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.
research Stem-Cell Therapy in Dermatology: Challenges and Opportunities
Stem-cell therapy shows promise for skin conditions but needs more research.
research DKK1 Mediated Inhibition of Wnt Signaling in Postnatal Mice Leads to Loss of TEC Progenitors and Thymic Degeneration
Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.
research The Promise and Challenges of Cell Therapy for Psoriasis
Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.
research Biological Significance of FoxN1 Gain-of-Function Mutations During T and B Lymphopoiesis in Juvenile Mice
FoxN1 overexpression in young mice harms immune cell and skin development.
research Human Clinical Phenotype Associated With FOXN1 Mutations
FOXN1 mutations cause severe immunodeficiency, hair loss, nail issues, and thymus defects.
research Corticosterone Inhibits GAS6 to Govern Hair Follicle Stem-Cell Quiescence
Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.
research FOXN1: A Master Regulator Gene of Thymic Epithelial Development Program
The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.
research P63 Targeted Deletion Under the FOXN1 Promoter Disrupts Pre- and Post-Natal Thymus Development, Function, and Maintenance, and Induces Severe Hair Loss
Deleting the p63 gene in certain cells causes problems in thymus development and severe hair loss in mice.
research Morphogenesis and Maintenance of the 3D Thymic Medulla and Prevention of Nude Skin Phenotype Require FoxN1 in Pre- and Post-Natal K14 Epithelium
FoxN1 gene is essential for proper thymus structure and preventing hair loss.
research The Paradox of p53: What, How, and Why?
The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.
research Apoptosis and Cutaneous Biology
Apoptosis is crucial for healthy skin and treating skin diseases.
research Sterol Intermediates of Cholesterol Biosynthesis Inhibit Hair Growth and Trigger an Innate Immune Response in Cicatricial Alopecia
Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.
research Analysis of Thymosin β4 and Vascular Endothelial Growth Factor Expression in Normal Human Tissues Using Tissue Microarray
Thymosin β4 and VEGF are important for blood vessel formation in many organs.
research Neuroimmunology of Stress: Skin Takes Center Stage
Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.
research Transient Mitochondrial DNA Double Strand Breaks in Mice Cause Accelerated Aging Phenotypes in a ROS-Dependent but p53/p21-Independent Manner
Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.