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This study reports that some human cell surface HLA-I molecules (including HLA-B27) can appear without their usual peptide component, potentially altering immune interactions, influencing arthritis development in specific mice models, and exhibiting upregulation in certain cancer cells.

This study reported that Taiwanese pre-teens and teenagers with atopic diseases, such as food allergies and asthma, had a significantly increased risk of developing alopecia areata, with the risk being 9.66 times higher compared to their peers without atopic conditions.

In this study, Luan et al. showed that epidermal stem cells play a key role in wound healing by coordinating the recruitment of regulatory T cells and neutrophils, which help balance immune tolerance and inflammation.

This study found that Aire‒/‒ mice spontaneously developed persistent AA-like lesions, highlighting a potential role for AIRE in hair follicle biology and pathogenesis of alopecia areata.

This review summarizes recent findings about the multi-site differentiation of tissue regulatory T cells, emphasizing the pivotal role of epigenetic remodeling, but it reports no new clinical results.

This study reviews the complexities of burn-related skin complications, highlighting postburn pruritus, dyspigmentation, and the risk of malignant ulcers, while offering a framework for evidence-based management through various treatment approaches.

This review discusses advancements in skin microphysiological systems, such as 3D bioprinting, skin organoids, and skin-on-a-chip, and their effectiveness in emulating human skin functions for research and preclinical applications, highlighting the potential for replacing animal testing with these innovative technologies.

This study found that regulatory T cells accumulate in hair follicle epithelium via the Cxcr4-Cxcl12 axis, partially influenced by glucocorticoid receptor signaling, promoting hair regeneration; similar mechanisms were observed in human and murine skin.

This review examines the interconnected processes of atopic dermatitis and alopecia areata, highlighting shared immune imbalances, genetic factors, and microbiome influences, while analyzing current and emerging treatments and identifying gaps in understanding these overlapping conditions.

This study found that injecting nu/nu mice with aqueous dispersion of unmodified fullerene C60 significantly stimulated hair growth compared to controls, suggesting its potential as a new therapeutic approach for alopecia.

This study highlights the role of abnormal DNA methylation in skin disorders such as atopic dermatitis and psoriasis, suggesting these epigenetic changes may serve as biomarkers and targets for potential treatments.

This literature review explores the role of biomarkers in personalized medicine for various dermatological conditions like Hidradenitis Suppurativa, Psoriasis, and Atopic Dermatitis, highlighting how they guide targeted therapies and the limitations of current markers in specificity, as reported by the authors.

This review discussed the cutaneous manifestations of APECED, highlighting chronic mucocutaneous candidiasis, alopecia areata, and vitiligo, while emphasizing the importance of early detection and monitoring for accurate diagnosis and patient care in various populations.

In this case report, significant improvements in a 58-year-old male with severe refractory myasthenia gravis and concurrent alopecia areata were observed following a cortisone taper, suggesting a potential therapeutic role, especially after thymectomy.

This study found that N,N-dimethylglycine sodium salt promoted proliferation and migration of cultured human epidermal keratinocytes and had anti-inflammatory and antioxidant effects in vitro.

In this study, researchers created a mouse model using CRISPR/Cas9 technology to investigate hypotrichosis simplex and woolly hair, finding that Krt71-knockout mice exhibited curly hair and developed complete hair shedding without immune deficiencies, mimicking conditions seen in humans and potentially aiding future hair disorder research.

This review reports that thermal spring waters, enriched with a diverse hydrobiome, hold promising potential for use in dermocosmetics, as their bioactive compounds could enhance skin protection, repair, and appearance, benefiting conditions like atopic dermatitis and rosacea.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

This review discusses the role of the long form of thymic stromal lymphopoietin in cutaneous immune-mediated diseases and reports no new results.

This study found that mesenchymal cells from different organs exhibit substantial heterogeneity, with thymic mesenchymal cells particularly adapted for interacting with epithelial and hematolymphoid cells in high-apoptosis environments.

This study presents evidence that specific thymus-derived peptides affect human hair follicle growth, identifying thymulin as a potential hair growth stimulator despite interindividual response variations.

This study found that thymic stromal lymphopoietin (TSLP) promotes hair growth after skin injury by enhancing the proliferation of specific stem cells in hair follicles.

This study found that 17beta-estradiol enhanced allergy responses in certain age groups of female mice and inhibited thymus involution and regeneration after contact hypersensitivity.

This study reported that in mice with rapamycin-induced thymic atrophy, Angelica sinensis promoted thymic cortical regeneration and functional recovery by activating the Wnt/CTNNB1/Foxn1 signaling pathway and improving inflammatory microenvironment, suggesting its potential benefit against immune aging.

This report discusses a potentially underdiagnosed form of multisystem Langerhans cell histiocytosis in infants, demonstrating the use of thymic sonography for staging, highlighting a case where thymic and cutaneous involvement was confirmed, and suggesting thymic ultrasound may aid in better diagnosis and management of LCH.

This study found that locally administering thymic stromal lymphopoietin (TSLP) promotes hair growth by stimulating hair follicle cell proliferation during both normal conditions and after skin injury in mice.

Thymic peptides can either promote or inhibit human hair growth.

This abstract provides funding and institutional support information but reports no new research findings.

In this study, rat primary thymic epithelial cells demonstrated a clonogenic growth pattern in vitro and were able to integrate into functional thymus or differentiate into skin derivatives, similar to skin multipotent stem cells.

This study presents a new mouse model for investigating chronic graft-versus-host disease, highlighting the role of human thymic tissue in developing multiorgan fibrosis driven by human immune cells.