288 citations
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January 2001 in “Journal of Biological Chemistry” In this study, the disruption of Gh/tissue transglutaminase in mice did not affect viability but reduced thymocyte viability and fibroblast adhesion, suggesting its role in cell stabilization and extracellular matrix interactions.
This study found that IL18 signaling plays a crucial role in the homing and retention of mature regulatory T cells in the mouse thymus, primarily by upregulating the chemokine receptor CCR6.
February 2024 in “Journal of medical science and clinical research” This case study reports a near-complete response of a proliferating trichilemmal tumor to neoadjuvant radiotherapy in a 79-year-old woman, highlighting radiotherapy's role in managing this condition when patients are unsuitable for surgery.
January 2007 in “Journal of The American Academy of Dermatology” Propylthiouracil, a thyroid medication, can cause skin blood clots and immune-related blood vessel inflammation.
December 2014 in “Journal of Biomedical Research” In a mouse model of peripheral vascular disease, this study found that recombinant thymosin β4 treatment increased expression levels of certain proteins, promoting angiogenesis.
January 2025 in “Open Veterinary Journal” This case series reports that electrochemotherapy with intravenous bleomycin effectively resolved cutaneous mast cell tumors in four cats, showing no tumor recurrence during follow-up, except for new lesions in one cat, and minimal local toxicity.
October 2025 in “Journal of the Endocrine Society” This case report documented the management of a 46-year-old female with Marine-Lenhart syndrome, combining antithyroids with minimally invasive sclerotherapy to achieve euthyroidism and reduce thyroid nodule size by 58%.
July 2023 in “Indian Journal of Endocrinology and Metabolism” This case study reports that carbimazole therapy led to significant hair regrowth and a drop in thyrotropin receptor antibody levels in an 11-year-old girl diagnosed with alopecia areata and Graves' disease.
80 citations
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August 1991 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” This study found that low-dose methotrexate significantly reduced the steroid requirement in subjects with corticosteroid-requiring asthma without altering their clinical status or causing significant complications.
9 citations
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November 2022 in “Journal of Cosmetic Dermatology” Among patients treated at Thomas Jefferson University, this study found that adding cryotherapy to intralesional triamcinolone acetonide (IL TAC) was more effective at reducing keloid size compared to IL TAC alone, although both treatments similarly eased pruritus and pain.
10 citations
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December 2018 in “Internal Medicine” This study reports two cases of myasthenia gravis patients with thymoma who exhibited various autoimmune symptoms including alopecia, suggesting a link between thymus-related immune dysregulation and comorbid conditions.
10 citations
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February 2019 in “The New England Journal of Medicine” This abstract discusses the importance of controlling visible abdominal tumors in women with ovarian cancer to improve survival, and notes that nonvisible microscopic tumors are then targeted with chemotherapy; it reports no new results.
November 2025 in “JOURNAL OF EXPERIMENTAL ZOOLOGY INDIA” This study observed that thymol from Origanum marjoram essential oil significantly promoted hair regrowth and reduced inflammation in cyclophosphamide-induced alopecia in rabbits, with effects that were comparable to or exceeded those of betamethasone, highlighting its potential as a safer treatment alternative.
6 citations
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July 2013 in “Archives of Plastic Surgery” This article explains that proliferating trichilemmal tumors, originating in the hair follicle, can exhibit low-grade malignant potential, and recommends wide excision to minimize recurrence risk, but reports no new clinical findings.
April 2020 in “Journal of the Endocrine Society” In this case report, successful management of a pituitary macroadenoma was achieved with thyroid hormone therapy, leading to reduced tumor size and improvement in symptoms like galactorrhea and headaches.
15 citations
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August 2002 in “British Journal of Ophthalmology” This paper discusses a case where intralesional cidofovir successfully treated squamous cell carcinoma without systemic toxicity, but surgical excision remains the standard for curative treatment and margin evaluation.
December 2025 in “Journal of Integrated Standardized Homoeopathy” This case report describes the use of individualized homoeopathic treatment and dietary modifications to manage hypothyroidism in a 23-year-old woman, resulting in symptom improvement and normalized TSH levels after tapering off levothyroxine.
12 citations
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December 2022 in “Current Protein and Peptide Science” This review discusses the molecular mechanisms and clinical applications of thymosin β4, highlighting its potential benefits for inflammation, wound healing, tumor metastasis, and other medical conditions but reports no new experimental results.
17 citations
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December 1951 in “Experimental biology and medicine” In this study of immature male albino rats on a vitamin B12-deficient diet, vitamin B12 supplementation improved body, hair, and thymus growth more effectively than aureomycin when countering the negative effects of cortisone.
January 2024 in “Wiadomości Lekarskie” This study reviews modern treatment techniques for large, life-threatening pulmonary emboli and concludes that pulmonary artery thrombectomy is a safe and effective method, though it remains underutilized. Results are not reported in the abstract.
May 2005 in “Cancer Research” This study found that over-expression of thymosin beta-4 in transgenic mice accelerated wound healing and hair growth, but did not affect tumor progression despite stimulating tumor metastasis.
October 2024 in “Journal of the Endocrine Society” This case report highlights that a patient with resistance to thyroid hormone was misdiagnosed as having Graves’ disease, leading to unnecessary radioactive iodine treatment.
November 2023 in “International surgery journal” In this case study, a 69-year-old male with a neck swelling was diagnosed with a trichilemmal cyst, highlighting the importance of complete surgical excision for lesions with proliferative or malignant potential.
April 2010 in “The journal of immunology/The Journal of immunology” This study found that deleting the FoxN1 gene in mice disrupted the 3D thymic epithelial structure and led to 2D epithelial cysts, revealing its crucial role in thymus organization but not causing athymia.
This observational study reviewed thyroid eye disease patients treated with teprotumumab at one center, reporting common side effects like fatigue and dry eye symptoms, with serious adverse events including two cases of blood clots and one pulmonary embolism.
May 2016 in “Endocrine Abstracts” The removal of the adrenal tumor improved the patient's symptoms and reduced androgen levels, indicating successful surgery.
3 citations
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February 2022 in “Canadian Medical Association Journal” This case report describes a 72-year-old man who developed symptoms of fatigue and cold intolerance after discontinuing his levothyroxine treatment for hypothyroidism six months earlier.
July 2024 in “Journal of Investigative Dermatology” Targeting TCR-Vβ2 in cutaneous T cell lymphoma shows promise for safer, more specific treatment.
April 2018 in “Dermatologic Surgery” This overview describes the Dermatologic Surgery journal's comprehensive coverage of dermatologic surgical procedures, but it reports no new research findings.
January 2019 in “Jui rinsho hifuka” This study reported that a 12-year-old neutered male Siberian husky dog showed resolution of alopecia, pyoderma, and diarrhoea after thyroidectomy and thyroid supplementation for a functional thyroid carcinoma.