Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study reviews recent advancements in microneedles made from PLGA, highlighting their use in delivering vaccines, drugs, and proteins through the skin with minimal invasiveness, and discusses the challenges and future potential of these delivery systems.

This review discusses the anticancer properties of ginseng, including its potential to alleviate chemotherapy side effects, and calls for more research on its mechanisms of action in various cancers.

This review examines around 68 plant sources from six major plant families, assessing their scientific rationale and use by the cosmeceutical industry for applications like anti-ageing and sun protection.

This review discusses the paracrine properties of cardiac stem cells and pericytes in regenerative medicine for ischaemic diseases and reports no new clinical results.

This review discusses various applications of CRISPR-based tools in cancer research, emphasizing their potential for investigating microRNA functions and developing microRNA-based therapies, despite challenges like off-target effects and delivery issues in using CRISPR/Cas9.

This review discusses current stem cell technologies, their potential therapeutic uses, and imaging techniques for tracking transplanted cells, without reporting new experimental results.

In this study, algal oligosaccharides effectively countered key factors in androgenetic alopecia pathogenesis, improving hair growth indicators in vitro and in mice.

This article reviews the possible therapeutic activities of Angelica gigas Nakai root extracts and their components, noting their potential effects on neuro-cognitive, metabolic, and other health conditions, and reports no new clinical results.

This study found that in a mouse model of bronchopulmonary dysplasia, minoxidil administered at 50 mg/kg/day did not impact lung development or inhibit lysyl hydroxylation.

In this study, low-dose oral minoxidil was found to have a favorable safety profile for treating alopecia, with mostly mild side effects, in both general and hypertensive populations.

This study found that all examined biomarkers and clinical features were elevated in systemic lupus erythematosus patients, particularly ANA and Anti-dsDNA autoantibodies, but no single biomarker was sensitive or specific enough for diagnosis.

This review discusses the potential of using SULT1A1 expression in the scalp as a biomarker to predict response to minoxidil treatment for androgenetic alopecia, but reports no new clinical results.

In this study, the researchers observed that biotin administration in biotin-deficient children with alopecia eliminated certain membrane proteins from their blood, suggesting that biotin might regulate these proteins' expression.

This study suggests that rat skin may synthesize minoxidil sulphate independently, implying the skin could contribute to minoxidil's hair growth promotion without help from the liver or other organs.

This article summarizes the properties, synthesis, and biomedical applications of molecules with N-oxide functionalities, emphasizing their growing role in healthcare due to their unique properties, such as water solubility and redox reactivity, crucial for drug targeting and cytotoxicity.

This study demonstrated that regular use of LactoSporin cream for 10 weeks significantly reduced wrinkles and fine lines in healthy female participants, although improvements in skin elasticity and hydration were not significantly better than placebo when measured by certain instruments.

This review examines the efficacy and safety of using minoxidil at concentrations greater than 5% for androgenetic alopecia but reports no new clinical results, emphasizing a need for further research.

This study used cryoelectron microscopy to unveil the structure of LPA-bound human LPAR6, revealing unique ligand binding and recognition modes distinct from LPAR1, which may aid in designing targeted compounds for hair loss and cancer.

This review discusses recent advances in protein immobilization on bacterial cellulose for various biomedical uses and reports no new clinical results.

In this review, various expression systems for synthesizing recombinant collagen are compared, highlighting their efficiency, modification capabilities, and cost. Key purification techniques are also analyzed, and challenges like reducing R&D costs and improving safety protocols are identified.

This study found that an anti-atopic lotion containing fucoidan helped heal skin damage in hairless mice with atopic dermatitis by reducing skin thickness and modulating immune responses.

This study found that keratin 15 expression is downregulated in hyperproliferative conditions like psoriasis and hypertrophic scars, suggesting it is not compatible with keratinocyte activation.

This review explores how microneedles can improve the delivery of dermatological treatments by bypassing the skin's outer barrier, discussing their potential use in managing skin diseases, cosmetic applications, and challenges related to clinical adoption.

This review discusses the design, properties, and potential applications of smart microneedles, with no new clinical results presented.

This study identified morphotype-specific gene expression patterns in feathers, enhancing understanding of the molecular and cellular processes involved in feather development and diversification.

This review explores the use of topical and transdermal delivery for drugs and cosmetics, highlighting the benefits of avoiding side effects and rapid metabolism, with a focus on nanoparticulate formulations and techniques for studying skin penetration.

This study explores the potential of seaweeds as a source of bioactive compounds for food, cosmetics, and medical applications, while highlighting concerns about toxic element accumulation and suggesting purification and nanoencapsulation techniques to enhance safety and stability.

This review discusses the pharmacological actions and potential therapeutic benefits of ginsenoside compound K for metabolic disorders, reports no new clinical results, and suggests further research on its bioavailability and toxicity.

This review explores the potential of self-amplifying RNA technology for protein replacement therapy in various health disorders but reports no new experimental results, indicating challenges remain for clinical approval.

This study investigated the effects of the 60% alcohol extract from Alnus sibirica and its active compound, oregonin, on hair health, observing anti-oxidative and anti-apoptotic benefits in human hair dermal papilla cells exposed to oxidative stress, suggesting potential as natural materials for hair loss prevention.