research Primary Cicatricial Alopecias
The document concludes that early diagnosis and treatment are crucial for managing rare hair loss disorders and that more research is needed to improve treatment strategies.
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510-540 / 1000+ results research Anti-Androgens in Hirsutism
Cyproterone acetate effectively treats hirsutism and related conditions.
research Transforming Growth Factor-β Signaling-Mediated Wound Healing Is Required for Hair Follicle Neogenesis
TGF-β signaling is essential for new hair growth after wounds.
research Stem Cell Therapy in Androgenetic Alopecia: A Review of Dermatology Literature from 2012 to 2022
Stem cell therapy shows promise for treating hair loss in androgenetic alopecia.
research The British Hair and Nail Society Presents a Review of Our National Grand Round of Challenging Hair Disorders and the Benefits to the Wider British Association of Dermatologists Membership
The review helps improve diagnosis and treatment of challenging hair disorders.
research Central Centrifugal Cicatricial Alopecia And Fibroproliferative Disorders: Exploring The Association With Uterine Leiomyomas
Black women with CCCA are more likely to have uterine fibroids.
research Trichoscopic Findings in Children and Adults with Alopecia Areata: A Comparative Study
Children with alopecia areata have more exclamation mark hairs and fewer yellow dots than adults.
research Regulatory γδ T Cells Protect Human Scalp Hair Follicles From Alopecia Areata In Vivo
γδTregs can protect hair follicles from alopecia areata and may help regrow hair.
research Citrullination at the Inflammatory Skin Barrier
A potential treatment for atopic dermatitis could be to increase PADI1 expression to improve skin barrier function.
research Interferon-24 Regulates the Expression of MMP1 and Dermal Collagen of the Skin
IL-24 contributes to skin aging by increasing collagen-degrading enzymes and decreasing collagen production when exposed to air pollution.
research DKK2 and SOSTDC1 Cooperate to Initiate the First Catagen Phase of the Hair Follicle Growth Cycle
DKK2 and SOSTDC1 together are necessary for the normal timing of the first regression phase in the hair growth cycle.
research Deregulation of Toll Like Receptor Signaling and Association With Caveolin-1 in Lichen Planopilaris Reveals a Novel Mechanism in Pathogenesis of Scarring Alopecia
The study suggests that changes in immune system receptors and their interaction with a cell component may be important in the development of a type of hair loss condition.
research Loss of UBE2N in Keratinocytes Leads to Skin Inflammation and Immune Infiltration Through IRAK1/4-Mediated Processes
Removing UBE2N from skin cells causes inflammation and immune response, which can be lessened with specific inhibitors.
research Single-Cell RNA Sequencing Reveals POUF51 and HES3 as Regulators of the Stem Cell Population in Psoriasis
POUF51 and HES3 are key in controlling stem cell numbers in psoriasis.
research MTORC1 Activity Is Increased in the Skin of Acne Patients and Is Suppressed With Isotretinoin Treatment
Acne patients have higher skin mTORC1 activity, which is reduced by isotretinoin treatment.
research Clinicopathological Characteristics of Fibrosing Alopecia in a Pattern Distribution: A Single-Center, Retrospective Study
The study suggests fibrosing alopecia in a pattern distribution has distinct features and may vary by race.
research Epidermal Growth Factor Receptor Protects From Immune Privilege Collapse and Scarring Hair Follicle Destruction
Blocking EGFR can lead to hair loss due to inflammation and stem cell damage.
research Janus Kinase Inhibitor Increases Hair Growth by Increasing Beta-Catenin Activity in Outer Root Sheath Cells
JAK inhibitors help hair growth by boosting beta-catenin activity in hair root cells.
research Single-Cell Transcriptomic Profile of EGFR-Deficient Epidermal Compartments During Folliculitis
EGFR deficiency causes significant changes in skin cells and hair follicles.
research Decreased IL-10 Producing Regulatory B Cells in Patients With Alopecia Areata
People with alopecia areata have fewer IL-10 producing immune cells, which might contribute to the condition.
research The Possible Role of PTEN-Induced Kinase 1-Mediated Mitophagy in Regulating Inflammasome Activation in the Pathogenesis of Alopecia Areata
Activating mitophagy may help manage a key immune response involved in the hair loss condition alopecia areata.
research Therapeutic Management of Generalized Canine Demodicosis With Secondary Bacterial and Yeast Infections: A Case Report
The dog fully recovered one month after treatment.
research Human Hair Follicles Can Taste: Stimulation of the Bitter Taste Receptor TAS2R4 Inhibits Hair Growth Ex Vivo by Up-Regulating TGF-β2
Activating a bitter taste receptor in hair follicles can stop hair growth by increasing a specific growth factor.
research Deciphering Pathomechanisms in Solar Urticaria
The study found that skin inflammation and immune response pathways are activated in Solar Urticaria patients after UV exposure, unlike in healthy people.
research Hunting the Hair Cycle Clock: Evidence That Mitochondrially Localized MPZL3 Is a Key Element in Murine and Human Hair Follicles
MPZL3 is important for controlling the hair growth cycle in mice and humans.
research A Novel Link Between Human Hair Follicle Neuroimmunology and Mitochondrial Biology: Substance P Increases Intrafollicular Oxidative Stress and Mitochondrial Biogenesis
Substance P may contribute to hair loss by increasing oxidative stress and mitochondrial activity in hair follicles.
research Loss of TET2 Tips the Scales Toward Tumorigenesis
Loss of TET2 increases the risk of skin and oral cancer.
research Botanical Extracts in Combination Improve Autosomal Recessive Woolly Hair/Hypotrichosis Caused by LIPH Mutations
Botanical extracts can help treat hair loss in people with certain genetic conditions.
research Localized Acquired Alopecia Over the Mental Area of Chin
A 12-year-old boy has a rare, harmless hair loss on his chin with no need for treatment.
research ILC1-Like Innate Lymphocytes in Human Autoimmunity: Lessons from Alopecia Areata
ILC1-like cells can cause alopecia areata by disrupting hair follicle immunity, suggesting a new treatment approach.