Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This paper reviews current and developing treatments for severe alopecia areata but reports no new clinical findings; the authors highlight the need for standardized treatment protocols.

The document concludes that various dermatological treatments and drugs can cause skin reactions and side effects.

This article reviews the impact of psychological factors on skin health and discusses the interplay between stress, the brain, and the immune system but presents no new clinical findings.

In this study, human gingival mesenchymal stem cells responded differently to inflammation mediated by oxidized low-density lipoprotein (oxLDL) compared to cytokines; oxLDL significantly reduced cell proliferation but had less negative impact on differentiation characteristics.

This article reviews treatment options for Alopecia Areata, concluding that topical corticosteroids are effective for mild cases, while systemic therapies are advised for moderate to severe cases.

This study found that patients with chronic kidney disease-associated pruritus had elevated serum levels of interleukin 31, suggesting a possible role of this cytokine in the condition.

This article reviews alopecia areata as a chronic autoimmune disease affecting hair follicles and discusses its association with other autoimmune conditions, but provides no new clinical findings.

This source outlines various antiandrogen and androgen inhibitor drugs used to treat cutaneous disorders of hyperandrogenism, detailing their mechanisms, uses, dosages, and side effects, with emphasis on spironolactone, finasteride, dutasteride, and oral contraceptives.

In this study, botulinum toxin type A injections reduced the severity of treatment-resistant scalp psoriasis in more patients compared to placebo over a 12-week period.

This study found that obesity in women may impair endometrial stromal function and contribute to reproductive complications, possibly due to metabolic influences rather than immune cell differences.

This article discusses the anatomical and biological aspects of hair follicle stem cells in the bulge region but reports no new research findings.

This study found that serum prolactin levels were significantly higher in patients with psoriasis, alopecia areata, and vitiligo compared to healthy controls, and prolactin levels were also correlated with disease severity in psoriasis and alopecia areata patients.

This narrative review highlights the shared immunopathogenesis of alopecia areata and atopic dermatitis and discusses approved and investigational therapies that target common pathways, suggesting a future for personalized treatment strategies.

This article reviews the emerging non-inflammatory roles of regulatory T cells in the skin and reports no new clinical findings, suggesting broad biological influence beyond traditional immune functions.

In this study, three patients with extensive alopecia areata receiving ustekinumab treatment showed significant hair regrowth and decreased inflammation over 20 weeks, suggesting potential targeted treatment for this condition.

This study found that certain genetic variations in the OPN gene may be linked to atopic dermatitis and a higher prevalence of asthma in Caucasians.

This article reviews the differences in inflammatory processes between alopecia universalis and atopic dermatitis, focusing on type 1 and type 2 immune responses, but it reports no new results.

This review summarizes the mechanisms of mesenchymal stem cell-mediated wound healing and highlights engineering strategies that enhance therapeutic outcomes, but it reports no new clinical results.

This review outlines how peptidyl arginine deiminases (PADIs) and protein citrullination are involved in hair follicle regeneration and inflammatory alopecia, but presents no new clinical findings.

This article reviews current and emerging treatments for alopecia areata, emphasizing the need for biomarker-driven patient stratification to optimize therapeutic strategies and reduce potential side effects; it reports no new clinical findings.

This study suggests that targeting adenosine receptors could be an effective strategy for reducing inflammation in inflammatory skin disorders, with promising results observed in animal models.

This review highlights that iron deficiency is a significant yet often overlooked contributor to the development of immune-mediated inflammatory skin diseases, suggesting that iron dysregulation may drive inflammation and metabolic imbalances in conditions like psoriasis and atopic dermatitis.

This study observed that while low vitamin D levels are associated with increased risk of autoimmune thyroid diseases, evidence from clinical trials on vitamin D supplementation shows inconsistent effects on thyroid function and disease progression, underscoring the need for further research.

This review examined 40 studies on exosome-based therapies for alopecia areata, reporting significant hair regrowth and improvements in hair count, length, and thickness, but highlighted the need for standardized methodologies and robust RCTs before clinical application.

This study found that the JAK1 inhibitors baricitinib and abrocitinib significantly reduced mechanical alloknesis in a murine model of atopic dermatitis, whereas the JAK2 inhibitor AZ960 had no effect.

This study developed a bioinspired hydrogel (BD@HH6) that exhibited strong antimicrobial and antioxidant properties, accelerated wound healing in mice by promoting angiogenesis and reducing inflammation, and represents a potential new approach for managing chronic wound infections without relying on antibiotics.

In this animal study, the researchers found that biodegradable extracellular matrix scaffolds accelerated wound healing and enhanced hair follicle neogenesis in mice, suggesting a role for immune systems in tissue regeneration.

This study suggests that antihistamines show promise as adjunct treatments for alopecia areata, but the role of dupilumab needs further investigation due to mixed results regarding hair regrowth and adverse effects.

This study found that coadministration of pimecrolimus may interfere with the therapeutic efficacy of mesenchymal stem cell therapy in atopic dermatitis.

In this study, thymic stromal lymphopoietin (TSLP) induced IL-4/IL-13 from T cells, prompting sebum secretion and adipose loss, suggesting IL-4/IL-13 may affect skin barrier function in atopic dermatitis.