Psychoneuroimmunology and Multifactorial Psychodermatological Diseases

The document discussed psychoneuroimmunology, a field studying the dynamic relationships between the brain, neuroendocrine, and immune systems through neuropeptides and hormones. It aimed to explain how mental and psychological factors affected the immune system and overall health. The skin played a critical role in immune functions, responding to internal and external stressors with highly coordinated cell communities. Psychological stress influenced diseases involving skin immune system cells and functions, creating complex interactions involving the brain, nervous system, and endocrine system, significantly affecting disease onset, progression, and treatment response. The article explored how psychogenic factors impacted the skin and activated various systems.