87 citations
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November 2016 in “Dermatologic Surgery” PRP shows potential for treating female hair loss, but more research needed.
87 citations
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May 2005 in “Journal of Dermatological Science” Asiasari radix extract promotes hair growth and increases protein synthesis and cell proliferation.
86 citations
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December 2001 in “Experimental dermatology” Mutant mice help researchers understand hair growth and related genetic factors.
76 citations
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December 2018 in “Aesthetic Plastic Surgery” Platelet-rich plasma may help in skin and hair treatments, and with muscle and joint healing, but more research is needed to fully understand its benefits and limitations.
68 citations
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September 2018 in “International Journal of Molecular Sciences” Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.
68 citations
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December 2014 in “Cell Biochemistry and Function” Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
66 citations
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June 2015 in “Aesthetic Plastic Surgery” Platelet preparations generally show positive effects on wound healing and facial rejuvenation, but more thorough research is needed to confirm their effectiveness.
65 citations
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June 2003 in “EMBO journal” Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.
63 citations
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December 2013 in “Dermatologic Surgery” Platelet-Rich Plasma (PRP) increases the number of new hair follicles and speeds up hair formation.
57 citations
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January 2017 in “Journal of Dermatological Treatment” PRP therapy may effectively treat hair loss, but more research needed.
54 citations
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April 2019 in “Journal of cellular physiology” miR-218-5p helps skin and hair growth by targeting SFRP2 and activating a specific signaling pathway.
53 citations
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August 2010 in “Journal of Cellular Physiology” Mice without Vitamin D receptors have hair growth problems because of issues in the hedgehog signaling pathway.
52 citations
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January 2013 in “Journal of Dermatological Science” The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
46 citations
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December 2001 in “Journal of Endocrinology/Journal of endocrinology” FLRG and follistatin have different roles in wound healing.
45 citations
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September 2014 in “Cell Transplantation” Activin B improves wound healing and hair growth by helping stem cells move using certain cell signals.
44 citations
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June 2006 in “Biological & Pharmaceutical Bulletin” Androgen hormones cause hair follicle scarring in hair loss, and finasteride helps reduce it.
43 citations
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September 2017 in “Lasers in Surgery and Medicine” LED light therapy may help hair growth by activating certain cell pathways.
41 citations
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July 2010 in “Clinics in Dermatology” Smoking harms skin health, causing slower wound healing, more wrinkles, and worsening some skin conditions, but may protect against certain others.
39 citations
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November 2013 in “Journal of dermatological science” Hair microRNAs could be effective biomarkers for diagnosing scleroderma.
39 citations
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July 2007 in “Archives of Pharmacal Research” A tripeptide-copper complex may help hair grow by increasing cell growth and decreasing cell death.
35 citations
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August 2021 in “npj Regenerative Medicine” Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
34 citations
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August 2011 in “Journal of Natural Medicines” Puerariae Flos extract may help treat hair loss by blocking a hair loss-related enzyme and promoting hair growth.
32 citations
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July 2012 in “Stem Cells Translational Medicine” Vitamin D3 can help improve hair growth by enhancing the function of specific skin cells and could be useful in hair regeneration treatments.
32 citations
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January 2005 in “Advances in Biochemical Engineering / Biotechnology” Fetal wounds heal without scarring because of different biological factors, which could help improve adult wound healing.
29 citations
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March 2018 in “European Journal of Immunology” Regulatory T cells are essential for normal and improved wound healing in mice.
29 citations
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January 2004 in “Experimental Dermatology” Topical anthralin helped regrow hair in mice with a condition similar to human alopecia.
28 citations
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December 2020 in “Gene” The ITGB6 gene is important for tissue repair and hair growth, and mutations can lead to enamel defects and other health issues.
28 citations
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September 2017 in “Gynecological Endocrinology” Women with PCOS have higher levels of AMH in their blood and follicles, and this can help predict their risk of overreaction to fertility treatments.
27 citations
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January 2012 in “Current Topics in Microbiology and Immunology” Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.
26 citations
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January 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” Regenerative therapies show promise for treating vitiligo and alopecia areata.