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510-540 / 1000+ results![569 Hypoxic response of the expression of TGF-β2 and BMP4 in human dermal papilla cells](/images/research/7bc41417-3614-4c3a-a8d0-2b88467cd027/small/16815.jpg)
research 569 Hypoxic response of the expression of TGF-β2 and BMP4 in human dermal papilla cells
Low oxygen levels affect the behavior of certain proteins in human skin cells.
research 1342 Spatial transcriptome profiling reveals TGFβ-2 in hair follicle progenitor cells is a potential driver of androgenetic alopecia
![Transforming growth factor-β in stem cells and tissue homeostasis](/images/research/4d38f480-144e-4334-af2c-4d1b50204625/small/19469.jpg)
research Transforming growth factor-β in stem cells and tissue homeostasis
TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
![Towards Dissecting the Pathogenesis of Retinoid-Induced Hair Loss: All-Trans Retinoic Acid Induces Premature Hair Follicle Regression (Catagen) by Upregulation of Transforming Growth Factor-β2 in the Dermal Papilla](/images/research/04a93fba-b549-4c4b-95c2-595bcd9715d0/small/23248.jpg)
research Towards Dissecting the Pathogenesis of Retinoid-Induced Hair Loss: All-Trans Retinoic Acid Induces Premature Hair Follicle Regression (Catagen) by Upregulation of Transforming Growth Factor-β2 in the Dermal Papilla
All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.
![New Activators and Inhibitors in the Hair Cycle Clock: Targeting Stem Cells’ State of Competence](/images/research/3aaec16d-8735-4f5f-b2df-146e16b6124b/small/14596.jpg)
research New Activators and Inhibitors in the Hair Cycle Clock: Targeting Stem Cells’ State of Competence
The conclusion is that Fgf18 and Tgf-ß signaling could be targeted for hair loss treatments.
![The role of activins and follistatins in skin and hair follicle development and function](/images/research/291bf336-bb47-402a-8cc8-8bf4928d932d/small/12870.jpg)
research The role of activins and follistatins in skin and hair follicle development and function
Activins and follistatins, part of the TGFβ family, are crucial for hair follicle development and skin health, affecting growth, repair, and the hair cycle.
![An investigation of crosstalk between Wnt/β-catenin and transforming growth factor-β signaling in androgenetic alopecia](/images/research/acf0c4ca-64d6-4822-8d1c-3b538e28c106/small/3850.jpg)
research An investigation of crosstalk between Wnt/β-catenin and transforming growth factor-β signaling in androgenetic alopecia
Wnt/β-catenin and TGF-β pathways affect hair loss, and activating Wnt/β-catenin could be a potential treatment.
![Live imaging of Smad2/3 signaling in mouse skin wound healing](/images/research/f7cc6851-2b3c-4c62-9c0b-6470da65ecd2/small/35665.jpg)
research Live imaging of Smad2/3 signaling in mouse skin wound healing
Smad2/3-dependent TGF-β signaling increases during wound healing.
research Hairless Up‐Regulates Tgf‐β2 Expression via Down‐Regulation of miR‐31 in the Skin of “Hairpoor” (HrHp) Mice
HR protein causes abnormal hair cycles by increasing Tgf-β2 and reducing miR-31.
![Transforming growth factor-alpha immunoreactivity during induced hair follicle growth cycles in sheep and ferrets.](/images/research/b9fe5329-cd2a-4cda-96c3-3132165668e3/small/29706.jpg)
research Transforming growth factor-alpha immunoreactivity during induced hair follicle growth cycles in sheep and ferrets.
TGF-alpha is present in sheep and ferret skin and may affect hair growth without directly stimulating cell proliferation.
![Author’s reply to the comment on: “The effect of intradermal botulinum toxin on androgenetic alopecia and its possible mechanism”](/images/research/0b4ff973-df6d-44a2-8505-64c37481a99b/small/5012.jpg)
research Author’s reply to the comment on: “The effect of intradermal botulinum toxin on androgenetic alopecia and its possible mechanism”
Botulinum toxin affects hair follicles, inhibiting TGF-B1 secretion; more research ongoing.
![Mesenchymal–epithelial interactions during hair follicle morphogenesis and cycling](/images/research/34b1c5fa-5387-4fb7-9688-c3f07f78fe1e/small/19818.jpg)
research Mesenchymal–epithelial interactions during hair follicle morphogenesis and cycling
The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.
![Melanocyte stem cells: a melanocyte reservoir in hair follicles for hair and skin pigmentation](/images/research/0f655eb8-caae-4c68-87bf-c2541b5f85b2/small/19869.jpg)
research Melanocyte stem cells: a melanocyte reservoir in hair follicles for hair and skin pigmentation
Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
research The epidermis: rising to the surface
The document concludes that recent research has improved understanding of skin diseases and the balance between cell growth and differentiation in the epidermis.
![Bioengineering skin using mechanisms of regeneration and repair](/images/research/ecf13783-9c24-4eb9-8e3a-d35b950b8353/small/12876.jpg)
research Bioengineering skin using mechanisms of regeneration and repair
Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
![Cutaneous Scarring: Basic Science, Current Treatments, and Future Directions](/images/research/df99e283-6a5b-4e78-b493-d5597f3cabf2/small/19467.jpg)
research Cutaneous Scarring: Basic Science, Current Treatments, and Future Directions
New effective scar treatments are urgently needed due to the current options' limited success.
![A Hot New Twist to Hair Biology](/images/research/31df9622-34ef-42b5-b02c-cb2f967a3201/small/26760.jpg)
research A Hot New Twist to Hair Biology
Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.
![Differential Expression of Fibromodulin, a Transforming Growth Factor-β Modulator, in Fetal Skin Development and Scarless Repair](/images/research/a1db90e5-330c-46d7-8dbd-9207629d3e8d/small/20042.jpg)
research Differential Expression of Fibromodulin, a Transforming Growth Factor-β Modulator, in Fetal Skin Development and Scarless Repair
Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.
![What does the concept of the stem cell niche really mean today?](/images/research/59335026-e880-4ec9-83bf-6b00c58dcf49/small/35639.jpg)
research What does the concept of the stem cell niche really mean today?
Stem cell niches support, regulate, and coordinate stem cell functions.
![Molecular biology of hair morphogenesis: Development and cycling](/images/research/d8b379fd-b078-4373-b272-bd75dfaf7013/small/25079.jpg)
research Molecular biology of hair morphogenesis: Development and cycling
Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.
![Molecular basis of androgenetic alopecia: From androgen to paracrine mediators through dermal papilla](/images/research/450feeda-6149-4034-bc3a-179ae3c7f481/small/3004.jpg)
research Molecular basis of androgenetic alopecia: From androgen to paracrine mediators through dermal papilla
Male pattern baldness involves hormones and cell signals affecting hair growth.
![Thyroid Hormones Directly Alter Human Hair Follicle Functions: Anagen Prolongation and Stimulation of Both Hair Matrix Keratinocyte Proliferation and Hair Pigmentation](/images/research/00b1292e-18be-4167-a822-5045d5c98d3c/small/23218.jpg)
research Thyroid Hormones Directly Alter Human Hair Follicle Functions: Anagen Prolongation and Stimulation of Both Hair Matrix Keratinocyte Proliferation and Hair Pigmentation
Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.
![Ontogenetic Transition in Fetal Wound Transforming Growth Factor-β Regulation Correlates with Collagen Organization](/images/research/fee2add0-140a-4345-825d-fe62a27270eb/small/20030.jpg)
research Ontogenetic Transition in Fetal Wound Transforming Growth Factor-β Regulation Correlates with Collagen Organization
Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.
![GROWTH FACTORS IN HAIR ORGAN DEVELOPMENT AND THE HAIR GROWTH CYCLE](/images/research/f2e1dc67-7a99-4446-b3a8-9e9879250c6c/small/23292.jpg)
research GROWTH FACTORS IN HAIR ORGAN DEVELOPMENT AND THE HAIR GROWTH CYCLE
Growth factors are crucial for hair development and could help treat hair diseases.
![Targeting Wnt/β-Catenin Pathway for Developing Therapies for Hair Loss](/images/research/b6ec7bed-18f0-4483-9032-e4aa445b6708/small/19279.jpg)
research Targeting Wnt/β-Catenin Pathway for Developing Therapies for Hair Loss
Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.
![TNF superfamily in skin appendage development](/images/research/784f920f-c816-49e8-812d-6f5ad14e51f7/small/35659.jpg)
research TNF superfamily in skin appendage development
TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.
![Sericin hydrogels promote skin wound healing with effective regeneration of hair follicles and sebaceous glands after complete loss of epidermis and dermis](/images/research/ee9aecfd-1530-4820-a54f-300282990878/small/19472.jpg)
research Sericin hydrogels promote skin wound healing with effective regeneration of hair follicles and sebaceous glands after complete loss of epidermis and dermis
Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.
![Epidermal Development in Mammals: Key Regulators, Signals from Beneath, and Stem Cells](/images/research/1279e627-fb80-4fac-8a2a-e535a3e9b40a/small/19776.jpg)
research Epidermal Development in Mammals: Key Regulators, Signals from Beneath, and Stem Cells
Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
![Control of pelage hair follicle development and cycling by complex interactions between follistatin and activin](/images/research/28cf0a2d-a4f2-44a5-8692-b739dc540dcf/small/25733.jpg)
research Control of pelage hair follicle development and cycling by complex interactions between follistatin and activin
Follistatin helps hair growth and cycling, while activin prevents it.