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TET enzymes are important for skin and hair development by controlling gene activity in specific areas.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

Calcium is important for stem cell function and maintenance, especially in blood and skin cells.

The enzymes Tet2 and Tet3 are important for skin cell development and hair growth.

Tet2 and Tet3 enzymes are important for controlling hair growth and shape by affecting gene activity and DNA structure in hair follicles.

Tet2 and Tet3 enzymes are essential for controlling hair growth by affecting DNA demethylation and gene expression in mice.

Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.

The enzymes Tet1, Tet2, and Tet3 are important for the development of hair follicles and determining hair shape by controlling hair keratin genes.

Loss of TET2 increases the risk of skin and oral cancer.

Tet1/2/3 enzymes affect hair follicle cell development by influencing BMP signaling.

Runx genes are important for stem cell regulation and their roles in aging and disease need more research.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.

Researchers found 71 genetic regions linked to male pattern baldness, which account for 38% of its genetic risk.

Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.

Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.

Stem cells control their future role by changing ERK signal timing, affecting tissue regeneration and cancer.

Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.

The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.

Epigenetic mechanisms control skin development by regulating gene expression.

The document concludes that understanding dermal papilla cells is key to improving hair regeneration treatments.

Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.

The research identified key molecules that help hair matrix and dermal papilla cells communicate and influence hair growth in cashmere goats.

Cyclooxygenase-2 overexpression in mice skin causes hair loss like human androgenetic alopecia.

Mouse skin glands need healthy nerves to grow properly during hair growth phases.

Hair follicles repair 3D injuries using a 2D healing process.

Patients with Systemic Sclerosis have much higher levels of GDF-15, which could help predict organ involvement and guide treatment.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.