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    Glossary Testosterone Metabolism

    process of breaking down and converting testosterone in the body

    Testosterone metabolism refers to the process by which the body breaks down and converts testosterone, a key male sex hormone, into other substances. This involves enzymes that transform testosterone into dihydrotestosterone (DHT) and estradiol, which play crucial roles in various bodily functions, including hair growth and sexual development. Understanding this process is important for addressing conditions like alopecia, where DHT can contribute to hair loss.

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    1. Testosterone metabolites differentially maintain adult morphology in a sexually dimorphic neuromuscular system Developmental Neurobiology · 2009 · 25 citations
    2. Physiopathological role of the enzymatic complex 5α-reductase and 3α/β-hydroxysteroid oxidoreductase in the generation of progesterone and testosterone neuroactive metabolites Frontiers in Neuroendocrinology · 2020 · 18 citations
    3. Direct quantitative digital autoradiography of testosterone metabolites in the pilosebaceous unit: an environmentally advantageous trace radioactive technology Steroids · 1993 · 4 citations
    4. DIABETE E DOLORE: EFFETTO TERAPEUTICO DEI METABOLITI DEL TESTOSTERONE Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano) · 2014
    5. Testosterone metabolite nonessential for androgen effects Nature Reviews Endocrinology · 2012 · 2 citations
    6. Preparation of3H-labelled testosterone metabolites Journal of Labelled Compounds and Radiopharmaceuticals · 2007 · 2 citations
    7. Synthesis and Actions of 5α-Reduced Metabolites of Testosterone in the Nervous System Androgens · 2021 · 1 citations
    8. Androgenic effect of testosterone and some of its metabolites in relation to their biotransformation in the skin. 1982 · 11 citations
    9. 892 Behavior of the two circulating androgens testosterone and DHEA and their main intracellular metabolites in an androgen-sensitive sebocyte cell line Journal of Investigative Dermatology · 2019
    10. The Role of Non-Aromatizable Testosterone Metabolite in Metabolic Pathways Physiological Research · 2011 · 21 citations
    11. Verstärkter Haarwuchs unter Langzeittokolyse mit Fenoterol** unter Berücksichtigung von Testosteron, Androstandiol, Cortisol und ACTH* Geburtshilfe und Frauenheilkunde · 1980 · 9 citations
    12. Steroidomics for highlighting novel serum biomarkers of testosterone doping Bioanalysis · 2019 · 23 citations
    13. Testosterone Metabolism in Human Skin Cells in vitro and Its Interaction with Estradiol and Dutasteride Skin pharmacology and physiology · 2003 · 21 citations
    14. Detection of urine metabolites in polycystic ovary syndrome by UPLC triple-TOF-MS Clinica Chimica Acta · 2015 · 23 citations
    15. Effects of sex steroid hormones and their metabolites on neuronal injury caused by oxygen-glucose deprivation/reoxygenation in organotypic hippocampal slice cultures Steroids · 2016 · 24 citations
    16. Antiaging effects of equol: A unique antiandrogenic isoflavone metabolite and its influence in stimulating collagen deposition in human dermal monolayer fibroblasts Journal of the American Academy of Dermatology · 2005 · 2 citations
    17. Sex Steroids, Precursors, and Metabolite Deficiencies in Men With Isolated Hypogonadotropic Hypogonadism and Panhypopituitarism: A GCMS-Based Comparative Study The Journal of Clinical Endocrinology & Metabolism · 2014 · 46 citations
    18. Avaliação do impacto da redução significativa de peso pela dieta cetogênica de muito baixa caloria nos parâmetros metabólicos, inflamatórios, hormonais e seminais de homens obesos 2023
    19. Expressão gênica da aromatase em folículos pilosos do vértice do escalpo de mulheres com ciclos ovulatórios e pacientes com síndrome dos ovários policísticos (PCOS) : análise de associação com parâmetros hormonais e metabolicos LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) · 2008
    20. Urinary steroids in men with male-pattern alopecia Journal of Biochemical and Biophysical Methods · 2002 · 13 citations
    21. What does the research say about androgen use and cerebrovascular events? Therapeutic advances in drug safety · 2018 · 5 citations
    22. 5α-Metabolism in Finasteride-Treated Subjects and Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency European Urology · 1991 · 8 citations
    23. Clinical and Biochemical Parameters of Androgen Action in Normal Healthy Caucasian<i>Versus</i>Chinese Subjects The Journal of Clinical Endocrinology & Metabolism · 1991 · 177 citations
    24. Assessment of Circulating Sex Steroid Levels in Prepubertal and Pubertal Boys and Girls by a Novel Ultrasensitive Gas Chromatography-Tandem Mass Spectrometry Method The Journal of Clinical Endocrinology & Metabolism · 2009 · 169 citations
    25. A randomized placebo-controlled study on the effects of pioglitazone on cortisol metabolism in polycystic ovary syndrome Fertility and sterility · 2008 · 24 citations
    26. Anti-androgenic potential of the fruit extracts of certain Egyptian <i>Sabal</i> species and their genetic variability studies: a metabolomic-molecular modeling approach Food & Function · 2022 · 1 citations
    27. Nonscarring alopecias CRC Press eBooks · 2015 · 3 citations
    28. Hair Restoration CRC Press eBooks · 2007
    29. Re: The association of urolithiasis and androgenetic alopecia. Resorlu M, Sancak EB, Uysal F, Arslan M, Diri A, Adam G, Akbas A, Sariyildirim A, Gulpinar MT, Resorlu B. Ren Fail. 2015 Oct 13:1–5 Renal Failure · 2016
    30. Androgenetic alopecia 2007