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Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Aromatase gene variation may increase female hair loss risk.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

Low level laser therapy works best for hair loss, followed by PRP, finasteride, and minoxidil.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

The effects of estrogen on human hair growth are unclear and need more research.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Women with polycystic ovary syndrome tend to have a longer distance between the clitoris and anus.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Certain genetic variations in the SHBG gene are linked to an increased or decreased risk of PCOS in Mediterranean women.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Hormones, nutrition, and seasonal changes regulate hair growth cycles, with androgens extending growth phases and factors like aging and malnutrition affecting hair loss and thinning.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

Hair loss requires customized treatments based on its various causes and types.

The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.

Stress and emotional factors can worsen skin conditions by affecting the immune system.

Sex hormones affect brain injury differently in males and females.

Men with benign prostatic hyperplasia are more likely to have metabolic syndrome than those without it.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Acne is common in women, often hormone-related, negatively affects quality of life, and requires various treatments.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

Low and ultralow doses of flutamide can cause liver damage in young women with high androgen levels, regardless of dose or birth control use, with higher risk for those with higher BMI and liver enzyme levels before treatment.