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Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.

Best results found using acetonitrile, water, and trifluoroacetic acid or methanol mixture.

Compound 15a was effective in inhibiting 5α-reductase.

Finasteride has different absorption and metabolism in male and female rats, with higher concentrations in certain organs and mostly excreted through feces.

RY-023, a specific drug, can improve early stage memory learning without affecting general activity in rats, but it's less effective for later learning stages and doesn't impact memory recall.

Finasteride forms three new products under acidic stress.

Finasteride effectively blocks enzyme causing male pattern baldness.

Researchers made two new compounds that could be used for medicine.

Method detects finasteride in plasma at very low concentrations.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Hair analysis can detect cocaine use but doesn't accurately show the amount or timing of use.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Mercuric triflate is an effective catalyst for various organic reactions, working well at room temperature with high yields.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

New treatments for Hepatitis C show promise but need more research to confirm their safety and effectiveness for clinical use.

Certain drugs that block specific enzymes can help treat prostate diseases.

Jojoba oil is highly valued for its diverse medicinal and industrial uses.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

The 3D electrospun fibrous sponge is promising for tissue repair and healing diabetic wounds.

Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.

Measuring reproductive hormones in brown bear hair could help identify their sex and reproductive state, but better collection methods or lab techniques are needed.

A natural steroid in the body may protect against eye damage in glaucoma.

Optimized film improves finasteride skin absorption and treatment efficiency.

New method detects finasteride in plasma quickly and accurately without clean-up.

Finasteride capsules with nanoparticles improve drug delivery, solubility, stability, and effectiveness.

Method can accurately measure five BPH drugs at once.