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330-360 / 1000+ resultsresearch Soy Protein Containing Isoflavones Improves Facial Signs of Photoaging and Skin Hydration in Postmenopausal Women: Results of a Prospective Randomized Double-Blind Controlled Trial
In this study, a 6-month randomized controlled trial with postmenopausal women reported that supplementing with soy protein isolate with isoflavones led to significant improvements in skin hydration and reduced wrinkles and facial pigment intensity, but did not affect sebum production.
research Treatment of periorbital aging with negative pressure fractional microneedle radiofrequency: A self‐controlled clinical trial
In this study, researchers found that negative pressure fractional microneedle radiofrequency significantly improved periorbital wrinkles, hydration, and dermal thickness in patients with periorbital aging, while also increasing orderly collagen and elastic fibers, with minimal adverse effects reported.
research The Auxin-Regulated CrRLK1L Kinase ERULUS Controls Cell Wall Composition during Root Hair Tip Growth
This study concluded that the receptor-like kinase ERULUS, regulated by auxin, is crucial for modulating cell wall composition and pectin dynamics during root hair growth in Arabidopsis.
research Epidermal mammalian target of rapamycin complex 2 controls lipid synthesis and filaggrin processing in epidermal barrier formation
mTORC2 is crucial for healthy skin barrier by regulating lipids and filaggrin.
research Identification and dissection of an enhancer controlling epithelial gene expression in skin
This study found that the HS III element in the K14 gene's regulatory sequence promotes gene expression in inner root sheath keratinocytes, highlighting cooperative interactions in keratinocyte-specific gene regulation.
research Enhanced Expansion and Sustained Inductive Function of Skin-Derived Precursor Cells in Computer-Controlled Stirred Suspension Bioreactors
In this study, using stirred-suspension bioreactors to expand dermal stem cells resulted in larger numbers, but had reduced efficiency in forming hair follicle structures compared to static culture conditions.
research Engineered Hair Follicle Mesenchymal Stem Cells Overexpressing Controlled-Release Insulin Reverse Hyperglycemia in Mice with Type l Diabetes
This study demonstrated that genetically engineered stem cells from human hair follicles can reverse hyperglycemia and reduce mortality in mice with type 1 diabetes by overexpressing the human insulin gene.
research The optimal holding solution and temperature for hair follicle grafts
This article discusses various holding solutions for hair transplant grafts and reports no new research findings; the authors emphasize the need for comparative studies.
research An LRH-RSL4 feedback regulatory loop controls the determinate growth of root hairs in Arabidopsis
A feedback loop between LRH and RSL4 controls root hair growth in Arabidopsis.
research Cryotherapy versus fractional carbon dioxide laser in patchy alopecia areata: a self-controlled comparative study
In this study, both fractional carbon dioxide laser therapy and cryotherapy were found to be effective and safe for treating patchy alopecia areata, showing similar efficacy in improving hair growth compared to untreated control patches.
research eLife Assessment: The Drosophila hematopoietic niche assembles through collective cell migration controlled by neighbor tissues and Slit-Robo signaling
In this study on Drosophila embryos, researchers observed that the Slit/Robo signaling pathway is crucial for the collective migration and proper positioning of Posterior Signaling Center cells within the hematopoietic niche, highlighting its role in niche assembly and cellular organization.
research A Randomized Double-Blind, Placebo-Controlled Study to Evaluate the Anti-Skin-Aging Effect of LactoSporin – The Extracellular Metabolite from Bacillus coagulans (Weizmannia coagulans) MTCC 5856 in Healthy Female Volunteers
This study demonstrated that regular use of LactoSporin cream for 10 weeks significantly reduced wrinkles and fine lines in healthy female participants, although improvements in skin elasticity and hydration were not significantly better than placebo when measured by certain instruments.
research Scalp Biophysical Characteristics in Males with Androgenetic Alopecia: A Comparative Study with Healthy Controls
This study found that men with androgenetic alopecia have different scalp biophysical characteristics in androgen-sensitive areas compared to non-sensitive areas and healthy controls.
research Anti-Particulate Adhesion Efficacy of a Cosmetic Product: A Controlled In Vivo Study Using a Patented Exposure Chamber
This study validated a new test method using a patented chamber to measure the efficacy of a sunscreen in reducing carbon black particle adhesion, with a 55% reduction observed on treated skin in a group of 22 women.
research The Vitamin D Receptor Is a Wnt Effector that Controls Hair Follicle Differentiation and Specifies Tumor Type in Adult Epidermis
This study observed that the vitamin D receptor is crucial for hair follicle formation and altering tumor development in the Wnt signaling pathway, suggesting therapeutic potential for vitamin D analogues in related tumors.
research Autotaxin–lysophosphatidic acid– LPA 3 signaling at the embryo‐epithelial boundary controls decidualization pathways
This study reports that the autotaxin–LPA–LPA3 signaling pathway at the embryo-epithelial boundary plays a critical role in decidualization by up-regulating HB-EGF and COX-2 in the uterine epithelium.
research The atypical ‘hippocampal’ glutamate receptor coupled to phospholipase D that controls stretch‐sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2
In this study, researchers identified the PLD-mGluR protein in primary mechanosensory terminals as the homomeric GluK2 kainate receptor, functioning purely metabotropically, which is suggested to be common to various sensory endings.
research Insights from Tandem Mass Tag (TMT) Proteomic Analysis on Protein Network Modification in Control of Yak Hair Follicle Cycle
This study identified key proteins, such as Sfrp1 and Ppard, involved in the complex and dynamic regulation of yak hair follicle growth and degeneration across different stages, offering insights into yaks' adaptation to highland environments.
research Designing a Placebo Microneedle Stamp: Modeling and Validation in a Clinical Control Trial
This study demonstrated that while the proposed placebo microneedle stamp design was partially successful in blinding participants with low skin sensitivity, further development of suitable placebo controls is needed.
research Synergistic delivery of ginseng exosomes and biomimetic melanosomes via temporally controlled hydrogel microneedles restrain the pathologic triad of vitiligo
This study developed a hydrogel microneedle system combining ginseng-derived exosomes and biomimetic nanoparticles to address oxidative stress, inflammation, and melanocyte deficiency in vitiligo, showing significant repigmentation in mice within 3 weeks by enhancing melanocyte protection and keratinocyte proliferation.
research An Innovative Formula for Keratosis Pilaris Treatment—A Randomized Controlled Study Based on the “Exfoliation‐Dissolution‐Repair” Concept
The new treatment improved keratosis pilaris symptoms and mood in 28 days.
research Synthesis of a new amino acid derivative with long‐lasting hair shape control effects and elucidation of its mechanisms
This study found that treating hair with ATS, formed from fumaric acid and cysteamine, effectively improved hair quality by increasing moisture content and altering the internal structure of strong curls.
research An oral French maritime pine bark extract improves hair density in menopausal women: A randomized, placebo‐controlled, double blind intervention study
In this study, oral Pycnogenol® intake was reported to significantly increase hair density and improve scalp microcirculation in Han Chinese menopausal women over six months.
research A randomized, double-blind controlled clinical study to evaluate the efficacy and safety of minoxidil topical 2% nanosuspension with aqueous base in the treatment of androgenetic alopecia areata
This study evaluated a new aqueous-based nanosuspension of minoxidil for treating androgenetic alopecia and reported it was as effective as the commercial product but had better safety and tolerability, potentially improving patient compliance.
research Skin and Scalp Health Benefits of a Specific Botanical Extract Blend: Results from a Double-Blind Placebo-Controlled Study in Urban Outdoor Workers
This study found that a 12-week regimen of a botanical supplement significantly improved skin and scalp health in women exposed to high pollution, enhancing factors like skin radiance, moisturization, and reducing wrinkle depth and scalp redness compared to a placebo.
research Forsythiae Fructus: A Review on its Phytochemistry, Quality Control, Pharmacology and Pharmacokinetics
This review discusses the phytochemistry, pharmacology, pharmacokinetics, and standardization of Forsythiae Fructus, detailing both unripe and ripe forms, but reports no new clinical results.
research Functional redundancy of Frizzled 3 and Frizzled 6 in planar cell polarity control of mouse hair follicles
This study found that Frizzled genes Fzd3 and Fzd6 are redundantly involved in controlling hair follicle polarity in mice, but operate through distinct mechanisms, highlighting their complex role in hair orientation.
research A Honey Trap for the Treatment of Acne: Manipulating the Follicular Microenvironment to ControlPropionibacterium acnes
This article suggests targeting the water activity within pilosebaceous follicles using biocompatible solutes like xylose and sucrose as a new potential topical treatment for acne.
research Mineral, trace element, and toxic metal concentration in hair from dogs with idiopathic epilepsy compared to healthy controls
This study found that dogs with idiopathic epilepsy had altered hair concentrations of several trace elements, which may suggest a role in the disease's pathophysiology and indicate effects from antiseizure medications.