3 citations
,
April 1997 in “Developmental Dynamics” In this study, topical trypsin treatment following depilation in a mouse model induced cell death at the follicular papilla, delaying hair growth and pigmentation.
5 citations
,
August 2005 in “Anatomy and Embryology” This study found that concentrated clusters of noradrenergic nerve fibers form a longitudinal linear system in rat skin, particularly innervating arrector pili muscles.
3 citations
,
January 2021 in “International journal of general medicine” This case report describes an 8-year-old boy with impetigenic scabies on his scalp, which responded well to treatment with topical permethrin, oral antihistamines, and antibiotics.
499 citations
,
September 2011 in “Cell” This study found that intradermal adipocyte lineage cells in mice are necessary and sufficient to activate follicular stem cells, highlighting their role in regulating skin stem cell activity.
24 citations
,
August 2019 in “Journal of the American Academy of Dermatology” Teledermatology reduces unnecessary in-person visits and improves care.
This chapter offers detailed histopathologic insights into various pilosebaceous unit diseases, discussing diagnosis without reporting new results.
21 citations
,
November 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that telogen, a resting phase of the hair follicle cycle, is characterized by dynamic gene expression, including enhanced cholesterol metabolism and immune signaling, suggesting it is an active regulatory phase despite its quiescent appearance.
1 citations
,
January 2024 in “Veterinary Dermatology” In this study, researchers cloned a two-year-old Pomeranian with Alopecia X after its accidental death and found that the cloned dog developed the same hair lesions at the same age, suggesting the condition is genetically driven rather than environmentally influenced.
July 2025 in “Journal of Investigative Dermatology” Secreted inhibitors of Wnt and IGF signaling control hair and tooth development, creating species-specific patterns.
9 citations
,
February 2016 in “Anatomical Science International” Hair proteins change location and structure as hair cells mature.
75 citations
,
January 2003 in “Journal of Investigative Dermatology”
1 citations
,
August 2019 in “Research Square (Research Square)” In this study, researchers found that the cashmere hair growth cycle is divided into three periods and key genes like KAP and KRTAP are positively correlated with these cycles in cashmere goats.
13 citations
,
February 2020 in “Cold Spring Harbor Perspectives in Biology” This review discusses the evolution of lineage-tracing strategies over the past century, emphasizing their role in identifying progenitor cells and resolving debates about cellular origins, with no new results reported.
142 citations
,
June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This workshop overview concluded that follicular epithelial stem cells are multipotent and located in the bulge region of hair follicles, contributing to hair, epidermis, and sebaceous gland formation.
83 citations
,
February 1991 in “Development” This study found that Fos protein expression is closely linked to epithelial cell differentiation, particularly during cornification and cell death, with overexpression observed in keratinization-blocked mutant epidermis.
35 citations
,
October 2002 in “Biochemical and Biophysical Research Communications” This study reports that K7 expression patterns observed in mice are similar to those in humans, revealing previously unreported expression in the gastrointestinal tract, tongue, and various "hard" epithelial tissues.
September 2025 in “Egyptian Journal of Dermatology and Venerology” This case study described the diagnosis of a trichofolliculoma in a 56-year-old woman, emphasizing its dermoscopic features and histological aspects that confirmed the tumor type, with no recurrence observed after excision.
74 citations
,
October 1998 in “Journal of biological chemistry/The Journal of biological chemistry” This study discovered nine human type I hair keratin genes, including a transcribed pseudogene, in a 190 kbp genomic region, revealing three gene subclusters based on sequence homologies.
7 citations
,
October 2022 in “Development Growth & Differentiation” This review summarizes recent insights into the developmental origin and formation of tissue stem cells across various organs, reporting no new experimental results.
4 citations
,
March 2022 in “Journal of The American Academy of Dermatology” Direct-to-consumer teledermatology is not effectively reaching underserved populations due to language, technology, and insurance barriers.
165 citations
,
September 2001 in “Genes & development” This study found that Cutl1 mutant mice experienced retarded lung differentiation and abnormal hair follicle morphogenesis, indicating the vital role of CDP in lung development and hair follicle cell-lineage specification.
3 citations
,
December 1967 in “Australasian Journal of Dermatology” This review discusses Becker's Melanosis and Hypertrichosis in young males, summarizing cases observed in Melbourne with clinical and histological analyses, but reports no new clinical findings.
1 citations
,
October 2025 in “Scientific Reports” This study investigated the Mandarin duck as a model for understanding lifelong developmental changes, finding that male sail feather morphogenesis involves a combination of local morphogenetic programs, epigenetic regulation, and hormonal cues, with increased female estrogen levels observed before the mating season.
6 citations
,
February 2022 in “The journal of neuroscience/The Journal of neuroscience” This study observed that deleting PTEN in mouse facial motoneurons enhanced peripheral axon regeneration but also led to physiological changes and potential hyperplasia in older mice.
10 citations
,
January 2001 in “ACTA HISTOCHEMICA ET CYTOCHEMICA” In this study, autophagy was commonly observed during keratinization in neonate rat hair follicles, suggesting lysosomal proteases and cytoplasmic enzymes may coordinate in hair follicle cell differentiation.
August 2012 in “Nature Cell Biology” This study provides direct evidence that the Wnt-β-catenin pathway promotes TERT expression in stem and cancer cells, linking tumorigenesis with pluripotency.
20 citations
,
August 2017 in “PLoS ONE” This study identified and updated the annotation of 61 keratin genes in dogs and horses, improving the genome annotation in these species through RNA-seq data comparison.
This review discusses the complex diagnosis and management of telogen effluvium, noting its high prevalence, psychosocial impact, and need for quantitative diagnostic techniques, but it reports no new research findings.
387 citations
,
November 2003 in “Journal of Investigative Dermatology” The K15 promoter effectively targets stem cells in the hair follicle bulge.
January 2016 in “Methods in molecular biology” This study identified a population of GFP-expressing nestin-positive cells in transgenic mice hair follicles that varied in location during different hair cycle phases, suggesting a shared relationship with neural stem cells.