research Role of Janus Kinase Inhibitors in the Treatment of Alopecia Areata
Janus kinase inhibitors show promise in treating alopecia areata but need better topical formulations.
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research Immunosuppressive Therapy in Autoimmune Disease: A Review
Immunosuppressive therapy helps manage autoimmune diseases but carries risks like infection and potential for malignancy.
research Cutaneous and Mucosal Lichen Planus: A Comprehensive Review of Clinical Subtypes, Risk Factors, Diagnosis, and Prognosis
Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.
research Genomewide Scan for Linkage Reveals Evidence of Several Susceptibility Loci for Alopecia Areata
Certain genes on chromosomes 6, 10, 16, and 18 may increase the risk of alopecia areata.
research CAQ Corner: Basic Concepts of Transplant Immunology
The document explains how the immune system reacts to organ transplants and the treatments used to prevent rejection.
research A Novel Therapeutic Paradigm for Patients with Extensive Alopecia Areata
New treatments targeting immune pathways show promise for severe hair loss but need more research for safety and effectiveness.
research Cutaneous Manifestations Associated With Immune Checkpoint Inhibitors
Immune checkpoint inhibitors can cause skin issues but are linked to better cancer outcomes.
research Alopecia Areata: Pathogenesis And Treatment
No single treatment is consistently effective for alopecia areata, and more research is needed.
research Identification of Drug-Specific Public TCR Driving Severe Cutaneous Adverse Reactions
Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.
research Discovery of Autoantigens in the Hair Loss Disorder Alopecia Areata: Implications of Posttranslational Modifications
Scientists are still unsure what triggers the immune system to attack hair follicles in Alopecia areata.
research Aldesleukin
Aldesleukin can treat certain cancers and increase HIV patient CD4+ counts but often causes severe side effects.
research Tissue Resident and Follicular Treg Cell Differentiation Is Regulated by CRAC Channels
CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.
research The Pathogenesis of Primary Cicatricial Alopecias
The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
research Frontal Fibrosing Alopecia: A Review
Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.
research Psoriasis Is Characterized by Deficient Negative Immune Regulation Compared to Transient Delayed-Type Hypersensitivity Reactions
Psoriasis may be chronic because it lacks certain immune system controls that prevent overreaction.
research Lymphocytic Mediated Alopecia: Histological Classification by Pattern Analysis
Steven Kossard classified lymphocyte-related hair loss into four patterns, each linked to different types of baldness.
research Role of Cytotoxic T Cells in Chronic Alopecia Areata
Cytotoxic T cells cause hair loss in chronic alopecia areata.
research Psychological Stress-Induced Pathogenesis of Alopecia Areata: Autoimmune and Apoptotic Pathways
Stress may contribute to hair loss in alopecia areata by affecting immune responses and cell death in hair follicles.
research Exploring Mast Cell–CD8 T Cell Interactions in Inflammatory Skin Diseases
Mast cells and CD8 T cells interact closely in skin diseases, affecting each other's behavior and contributing to conditions like psoriasis and eczema.
research Targeting Integrin Pathways: Mechanisms and Advances in Therapy
New therapies are being developed that target integrin pathways to treat various diseases.
research Hair Follicle Immune Privilege and Its Collapse in Alopecia Areata
Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.
research Fatal Autoimmunity Results from the Conditional Deletion of Snai2 and Snai3
Deleting Snai2 and Snai3 causes fatal autoimmunity.
research Regulatory T Cells: The Many Faces of Foxp3
Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.
research The Etiology and Pathogenesis of Alopecia Areata
The cause of alopecia areata is likely a mix of genetics, immune system issues, and environmental factors, with more research needed to understand it fully.
research Impaired Responses of Peripheral Blood Mononuclear Cells to T-Cell Stimulants in Alopecia Areata Patients with a Poor Response to Topical Immunotherapy
Poor response to topical immunotherapy in alopecia areata patients is linked to impaired cell responses.
research Pathophysiology of Behçet's Disease
Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.
research Immunological Aspects and Gender Bias During Respiratory Viral Infections Including Novel Coronavirus Disease-19 (COVID-19): A Scoping Review
Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.
research Alopecia Areata After Denosumab Treatment for Osteoporosis
Denosumab treatment for osteoporosis can cause hair loss.
research Wound Healing: A Cellular Perspective
The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
research Immune Modulation of Hair Follicle Regeneration
Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.