11 citations,
July 2022 in “Frontiers in Immunology” Four specific genes are linked to keloid formation and could be potential treatment targets.
11 citations,
October 2021 in “Stem Cell Research & Therapy” Hair follicle stem cells reduced hair loss and inflammation in mice with a condition similar to human alopecia.
35 citations,
December 2020 in “International Journal of Molecular Sciences” Mast cells likely promote skin scarring and fibrosis, but their exact role is still unclear.
16 citations,
October 2023 in “Molecular cancer” New treatments like nanotechnology show promise in improving skin cancer therapy.
3 citations,
December 2016 in “Springer eBooks” Activating TLR3 improves the healing and immune properties of periodontal ligament stem cells.
2 citations,
June 2023 in “Gels” Injectable hydrogels are becoming increasingly useful in medicine for drug delivery and tissue repair.
3 citations,
June 2023 in “Molecules/Molecules online/Molecules annual” Cepharanthine has many medicinal uses but needs improvement for better effectiveness.
21 citations,
January 2022 in “Biomaterials Science” RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.
4 citations,
May 2018 in “International Journal of Molecular Sciences” The research showed how melanocytes develop, move, and respond to UV light, and their stem cells' role in hair color and skin cancer risk.
1 citations,
March 2023 in “Phytochemistry Reviews” CBD may improve skin and hair health, but its effective use and safety need more research.
16 citations,
January 2018 in “International Journal of Trichology” Minoxidil may help treat hair loss by reducing inflammation-related gene activity in skin cells.
97 citations,
January 2020 in “Advances in chronic kidney disease” Calcineurin inhibitors, used in kidney transplants, can cause a wide range of side effects including kidney damage and other health issues.
8 citations,
July 2020 in “Clinical, cosmetic and investigational dermatology” Excessive sun protection might cause frontal fibrosing alopecia by disrupting skin immune balance.
February 2024 in “Skin health and disease” Many popular skincare products claim to prevent aging but lack strong evidence to prove their effectiveness and safety.
2 citations,
November 2023 in “Biomolecules” WNT signaling is crucial for skin development and healing.
April 2023 in “Dentistry” Baby teeth stem cells can potentially grow organs and treat diseases.
1 citations,
February 2024 in “Cosmetics” Cannabidiol shows promise as an effective treatment for acne.
4 citations,
December 2022 in “Frontiers in Bioengineering and Biotechnology” Exosomes show promise for improving wound healing, reducing aging signs, preventing hair loss, and lightening skin but require more research and better production methods.
2 citations,
October 2018 in “Springer eBooks” Cancer treatments can cause skin-related side effects that may affect patient quality of life and require changes in treatment.
9 citations,
May 2005 in “Expert Review of Clinical Immunology” Blocking interferon-gamma might help treat various autoimmune diseases.
60 citations,
May 2015 in “Archives of dermatological research” PPAR agonists show promise for skin conditions but need more research before being a main treatment.
December 2023 in “International journal of multidisciplinary research and analysis” SH-MSCs gel can effectively treat alopecia by increasing IL-10 and decreasing TNF-α gene expression.
1533 citations,
October 2008 in “Endocrine reviews” Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
229 citations,
August 2002 in “Experimental Gerontology” AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.
182 citations,
November 2017 in “Molecular Aspects of Medicine” The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.
40 citations,
January 2016 in “Elsevier eBooks” The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
11 citations,
September 1999 in “Journal of the European Academy of Dermatology and Venereology” Immunomodulatory therapies are effective for treating cutaneous lymphoma, particularly in early stages.
29 citations,
December 2012 in “Fibrogenesis & Tissue Repair” Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.
126 citations,
January 2009 in “International Journal of Trichology” Oxidative stress contributes to hair graying and loss as we age.
105 citations,
August 2010 in “Pharmacology & therapeutics” Formyl-peptide receptor agonists could be new anti-inflammatory drugs.