July 2026 in “Preprints.org” In this observational study, researchers found that new users of tirzepatide experienced a higher incidence of alopecia compared to semaglutide users over a 12-month period, with increased risk persisting even when accounting for achieved weight loss and treatment duration.
This review investigates the relationship between polycystic ovarian syndrome and the development of type 2 diabetes mellitus but reports no new clinical findings.
May 2022 in “Endocrine practice” This case report illustrates that high-dose biotin supplementation can cause false thyroid function test abnormalities in vitro, emphasizing the need to assess biotin intake before testing.
July 2023 in “Journal of Clinical Medicine” This study reviews current treatments for PCOS and evaluates Tirzepatide as a potential option for its management, suggesting possible benefits for those with obesity and metabolic syndrome but not for those of normal weight.
3 citations
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August 2025 in “International Journal of Molecular Sciences” This study found that women with PCOS have significantly higher prevalence and levels of thyroid autoantibodies, with these elevated levels suggesting a potential independent autoimmune activation associated with PCOS.
January 2025 in “Mansoura Medical Journal” This research observed that some hypothyroid patients on adequate levothyroxine therapy continue to experience symptoms like poor concentration and hair loss, with findings suggesting an elevated anti-TPO level increases the likelihood of such symptoms, despite normal TSH levels.
February 2009 in “Journal of The American Academy of Dermatology” Most patients with Tuberous sclerosis had neurological or skin issues, and over half had psychiatric problems.
January 2026 in “Case Reports in Rheumatology” This case report described a woman with systemic lupus erythematosus and Type 2 diabetes who developed dermatomyositis, showing improvements in muscle strength and creatine kinase levels following treatment with rituximab.
January 2026 in “Dermatology Reports” This case study reports that a 15-year-old male with multiple autoimmune conditions showed significant improvement in skin and gastrointestinal symptoms, along with hair regrowth, after 16 weeks of treatment with the JAK-1 inhibitor upadacitinib, demonstrating its potential in managing complex autoimmune disorders.
February 2022 in “Journal of Armed Forces Medical College” This case report details a patient with autoimmune hypothyroidism who experienced multiple health issues that improved with comprehensive treatment including Thyroxin replacement and other supportive measures.
15 citations
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January 2024 in “Chemical Engineering Journal” 18 citations
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January 2024 in “Regenerative Biomaterials” This study developed and tested a new injectable hydrogel for chronic diabetic wounds, reporting significant improvements in wound healing through enhanced angiogenesis, epithelization, and reduction of inflammation and infection in animal models.
April 2020 in “Journal of the Endocrine Society” In this case report, successful management of a pituitary macroadenoma was achieved with thyroid hormone therapy, leading to reduced tumor size and improvement in symptoms like galactorrhea and headaches.
December 1951 in “Journal of the American Medical Association” This article reports a case of hair loss and pigmentation changes in a man after using propylthiouracil alongside iodine solution for thyroid and diabetic conditions, providing clinical observations without broader conclusions.
99 citations
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June 2005 in “Endocrinology” This study found that applying supraphysiologic doses of topical T3 significantly accelerated wound healing in mice compared to a control vehicle, suggesting its potential as a cost-effective wound treatment.
November 2025 in “Journal of Investigative Dermatology” TEC kinases may help cause inflammation in vitiligo and could be targeted for treatment.
3 citations
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March 2019 in “Case Reports” This report highlights a case of possible association between myotonic dystrophy type 1 and basal cell carcinoma, urging clinicians to consider this link despite negative genetic testing for known hereditary BCC syndromes.
9 citations
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January 2017 in “Ginekologia Polska” This study found that the total testosterone/dihydrotestosterone ratio correlates with a negative metabolic profile in both women with PCOS and healthy women.
July 2022 in “International Journal of Health Sciences” This study assessed lipid parameters and serum DHT levels in type 2 diabetes patients, but the abstract does not specify the findings about their association.
1 citations
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February 2022 in “Clinical, Cosmetic and Investigational Dermatology” In this study, researchers found that the thyroxine receptor agonist TDM10842 accelerated the onset of anagen, a hair growth phase, in C3H mice, potentially through activation of the Wnt/beta-catenin and Hedgehog pathways, with Pclaf playing a key role in this process.
April 2026 in “Journal of Investigative Dermatology” This research observed that diabetes impairs wound healing in mice by disrupting key mechanotransduction pathways in fibroblasts, which are crucial for the healing process. The study also suggests transcriptomic changes could inform future diabetic wound repair therapies.
January 2004 in “Weiliang yuansu yu jiankang yanjiu” This study found that diabetic individuals had significantly lower hair levels of chromium, manganese, and copper, but higher iron levels, compared to non-diabetic controls.
13 citations
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August 2016 in “Medical Hypotheses” This review discusses the potential of evaluating hair follicle characteristics as early indicators of vascular impairment and organ damage in pre-diabetic individuals, but reports no new clinical results.
21 citations
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January 2005 in “Pediatric Dermatology” An 8-year-old girl with vitiligo developed extra hair growth on her knee after using tacrolimus ointment.
95 citations
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September 2019 in “Brain” In this study, two patients with refractory juvenile dermatomyositis improved clinically and in disease activity after receiving the JAK inhibitor tofacitinib, showing potential effects in managing the condition.
10 citations
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March 2015 in “Journal of dermatology” This case report describes a 12-year-old boy with severe skin scaling due to novel compound heterozygous null truncation mutations in the TGM1 gene, resulting in loss of transglutaminase 1 activity.
1 citations
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May 2022 in “European Journal of Dermatology” This study found that while no predictive factors for response to vismodegib were identified, longer treatment duration was associated with a lower risk of relapse in basal cell carcinoma patients.
1 citations
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December 2025 in “Journal of the American Academy of Dermatology” 7 citations
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March 2004 in “Journal of the American Academy of Dermatology” Tiger tail banding and hair abnormalities are reliable indicators for diagnosing trichothiodystrophy.
July 2026 in “Journal of the American Academy of Dermatology” Acanthosis Nigricans is the most common skin sign of insulin resistance.