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Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Humans lost body hair relatively recently in evolution.

Many patients experience long-lasting symptoms like fatigue and pain after COVID-19, regardless of initial disease severity.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Peptide hydrogels heal burn wounds faster and better than standard dressings.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

About 2.2% of women with symptoms of high male hormones have a mild form of congenital adrenal hyperplasia, and measuring a specific hormone level can accurately diagnose it.

Laser hair removal effectiveness depends on targeting hair structures without harming the skin, and improvements require more research and expert collaboration.

Scalp dermoscopy is good for diagnosing a type of hair loss and helps choose the best spots for biopsy.

Antiandrogens are somewhat effective in reducing excessive hair growth in women.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

miR-31 regulates hair growth by controlling gene expression in hair follicles.

Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.

Minoxidil works better for female hair loss, but cyproterone reduces scalp oiliness and causes menstrual issues.

Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.

Targeted cancer therapies often cause skin side effects, needing dermatologist care.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Mice without the vitamin D receptor are more prone to UV-induced skin tumors.

Baricitinib was effective in treating alopecia areata in two major trials.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Laser device increases hair density, safe for treating hair loss in men and women.

5α-reductase inhibitors may prevent prostate cancer but could also raise the risk of more severe cancers.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Cathepsin L is essential for normal hair growth and development.