Search
for

    Glossary T cell activation

    process where T cells respond to specific antigens

    T cell activation is the process by which T cells, a type of white blood cell, are triggered to respond to pathogens or infected cells. This occurs when T cells recognize specific antigens presented by other cells, leading to their proliferation and differentiation into effector cells that can directly attack infected cells or help coordinate the immune response.

    Related Terms

    Sort by

    Research 30 of 1000+

    1. Hair Follicle Mesenchyme-Associated PD-L1 Regulates T-Cell Activation Induced Apoptosis: A Potential Mechanism of Immune Privilege Journal of Investigative Dermatology · 2013 · 53 citations
    2. <i>In vivo </i>CD44‐CD49d complex formation in autoimmune disease has consequences on T cell activation and apoptosis resistance European Journal of Immunology · 2006 · 33 citations
    3. MicroRNA-1246 Inhibits NFATc1 Phosphorylation and Regulates T Helper 17 Cell Activation in the Pathogenesis of Severe Alopecia Areata 2023
    4. Resident T cell activation leads to human hair follicle immune privilege loss ex vivo, which is prevented by the DHODH inhibitor farudodstat: relevance for alopecia areata Frontiers in Medicine · 2026
    5. Image 1_Resident T cell activation leads to human hair follicle immune privilege loss ex vivo, which is prevented by the DHODH inhibitor farudodstat: relevance for alopecia areata.pdf Figshare · 2026
    6. Aberrant B cell and cytotoxic T cell activation in female pattern hair loss: a pilot comparative clinico-transcriptomic study Journal of Investigative Dermatology · 2025
    7. Attending persistent T cell activation in alopecia areata : A therapeutic option Repository KITopen (Karlsruhe Institute of Technology) · 2011
    8. Decision letter: Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of γδT-cells 2017
    9. 1349 Stimulation of hair follicle stem cell proliferation through an IL-1α dependent activation of γδT-cells 2018
    10. Antroquinonol Exerts Immunosuppressive Effect on CD8<sup>+</sup> T Cell Proliferation and Activation to Resist Depigmentation Induced by H<sub>2</sub>O<sub>2</sub> Oxidative medicine and cellular longevity · 2017 · 11 citations
    11. Author response: Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of γδT-cells 2017
    12. Regulatory T cells modulate bone marrow stromal cell osteogenesis by activating ROCK-myosin axis and cell contractility 2026
    13. Evaluation of the serum level of regulation upon activation of normal T-cell expressed and secreted protein in different types of alopecia areata 2015
    14. Morphologic and Histologic Comparison of Hypertrophic Scar in Nude Mice, T-Cell Receptor, and Recombination Activating Gene Knockout Mice 2015 · 9 citations
    15. Metabolic syndrome in androgenetic alopecia patients; Is serum regulated on activation, normal T‐cell expressed and secreted the missing link? Journal of Cosmetic Dermatology · 2020 · 1 citations
    16. Impaired responses of peripheral blood mononuclear cells to T-cell stimulants in alopecia areata patients with a poor response to topical immunotherapy 2008 · 4 citations
    17. 0034 Cross-species insights into hair follicle-T cell interactions in discoid lupus erythematosus: A comparison of human, canine and mouse models using spatial transcriptomics Journal of Investigative Dermatology · 2025
    18. TLR9 activation in large wound induces tissue repair and hair follicle regeneration via γδT cells Cell Death and Disease · 2024
    19. 0037 Inflammatory implications in female pattern hair loss: unraveling B cell-related immune activation through comparative transcriptome profiling Journal of Investigative Dermatology · 2025
    20. Soluble CD83 reverses alopecia areata via IDO-mediated Treg cell activation British Journal of Dermatology · 2026
    21. Gene Array Profiling and Immunomodulation Studies Define a Cell-Mediated Immune Response Underlying the Pathogenesis of Alopecia Areata in a Mouse Model and Humans Journal of Investigative Dermatology · 2002 · 114 citations
    22. TCL1 transgenic mouse model as a tool for the study of therapeutic targets and microenvironment in human B-cell chronic lymphocytic leukemia Cell Death and Disease · 2016 · 38 citations
    23. 0960 Evidence for resident memory T cells and necroptosis as drivers of fibrosis in eosinophilic fasciitis and morphea Journal of Investigative Dermatology · 2025
    24. 0150 Single-cell and spatial transcriptome profiling reveals innate-adaptive crosstalk in alopecia areata Journal of Investigative Dermatology · 2025
    25. 290 Brepocitinib improves cicatricial alopecia and downregulates key T-helper biomarkers Journal of Investigative Dermatology · 2024
    26. 164 Epigenetic and transcriptional profiling of PBMCs in mild and severe alopecia areata using single-cell RNA-Seq and ATAC-Seq Journal of Investigative Dermatology · 2023
    27. 1315 An Integrated model of alopecia areata biomarkers highlights both Th1/Th2 upregulation, with stronger correlations between Th2 activation and disease severity Journal of Investigative Dermatology · 2018
    28. Transcriptional profiling in alopecia areata defines immune and cell cycle control related genes within disease-specific signatures Genomics · 2010 · 61 citations
    29. Integrated single-cell chromatin and transcriptomic analyses of peripheral immune cells in patients with alopecia areata Frontiers in Immunology · 2025 · 4 citations
    30. Comprehensive single-cell transcriptomic profiling of the scalp from patients with moderate-to-severe alopecia areata Journal of Allergy and Clinical Immunology · 2026