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This study demonstrated that transcutaneous vaccination via cyanoacrylate skin surface stripping effectively induced both CD4 and CD8 T cell responses in humans, offering a promising alternative to intramuscular injection.

In this study, transcutaneously applied nanoparticles and viral vectors were shown to penetrate murine hair follicles, internalize in antigen-presenting cells, and induce immune responses, suggesting a promising approach for vaccine delivery.

This review discusses the molecular mechanisms by which oncogenic viruses contribute to cancer development through manipulation of host cellular functions and highlights the need for further research into virus-associated cancers, reporting no new results.

This study found that in lamivudine-resistant hepatitis B patients, tenofovir significantly reduced HBV DNA levels faster and more consistently than adefovir, reaching undetectable levels in all treated patients by 44 weeks.

This study found that transfollicular delivery using surfactant-based nanoparticles significantly enhanced antigen stability and immune response compared to other delivery methods, especially when combined with an adjuvant.

This case report describes a 6-year-old girl who developed MIS-C following COVID-19 vaccination, raising questions about the vaccine's potential role in its pathogenesis for children aged 5 to 11.

This study reported five cases of alopecia areata following COVID-19 vaccination, with one patient experiencing worsening symptoms with each vaccine booster.

In this case report, two plywood mill workers developed allergic contact dermatitis due to exposure to uncured phenol-formaldehyde resin, not sawdust as initially suspected.

This study reviews the evolution and modifications of microneedle drug delivery systems, initially designed for percutaneous use, now expanded for targeting a variety of tissues and organs such as ocular, oral mucosal, and gastrointestinal, suggesting widespread future applicability.

In this study, researchers reported that a newly developed interferon-γ release assay for cell-mediated immunity to SARS-CoV-2 nucleocapsid peptides demonstrated high sensitivity and specificity, making it a robust tool for routine diagnostic tests and potentially useful in predicting clinical outcomes after pathogen re-exposure.

This study found that patients with alopecia areata receiving ritlecitinib showed immune responses to meningococcal and tetanus vaccines, achieving significant antibody levels after vaccination, and no vaccine-related adverse events or disease exacerbations were reported despite a small sample size.

This report examines the cautious approach to administering live vaccines to an infant with a heterozygous FOXN1 variant, noting the importance of monitoring TREC levels and immune function indicators in guiding vaccination decisions in such cases.

This review discusses the relationship between aging, chronic inflammation, and immunosuppression, suggesting that these interconnected processes may contribute to tumorigenesis and premature aging, but reports no new experimental results.

This article reviews a variety of research presentations from the Society for Investigative Dermatology's annual meeting, highlighting advances in dermatological research without reporting new clinical results.

This review highlights the importance of promptly addressing symptoms in patients with inflammatory bowel disease, whether they stem from disease activity, medication side effects, or related autoimmune conditions, but it reports no new findings.

This review discusses the potential of microneedles to enhance transdermal drug delivery by expanding the range of deliverable drugs, highlighting fabrication methods, material choices, and applications, but notes existing challenges with sustained delivery, cost-effectiveness, and large-scale production.

This review reports that sex-related differences in pharmacological response have been observed in SARS-CoV-2 infection, dyslipidemia, and diabetes mellitus, with implications for treatment strategies; for example, men may respond better to genomic vaccines for SARS-CoV-2, while women may benefit more from certain antiviral medications.

This study highlights that biological therapy, which stimulates the immune system through various methods like cytokine injections and immune checkpoint inhibition, shows promise for treating melanoma based on laboratory and clinical studies.

This review discusses the dual role of tissue-resident memory T cells in providing immune protection against infections and cancer and contributing to autoimmune skin disease pathology, without presenting new experimental results.

This study found that γδ T cells in the skin contribute to wound healing after vaccinia virus infection by promoting cytokine and growth factor induction, without affecting virus replication control.

This review discusses the potential of microneedle arrays for drug delivery and in the cosmetic market, but reports no new clinical results; factors for commercial therapeutic use are explored.

This study found that COVID-19 vaccination initially lowered vitamin D levels in serum and hair but increased serum levels after the second dose, except for the Pfizer group. Hair vitamin D showed a nonsignificant increase, and hair loss was most common with the AstraZeneca vaccine.

This study investigates whether lymphocytes from mice with secondary alopecia areata can effectively induce the disease in a C3H/HeH mouse model, similar to lymphocytes from mice with spontaneous disease.

Hair loss may link to weaker COVID-19 immunity, suggesting possible need for extra vaccine boost.

This review discusses the impaired functionality of regulatory T cells in the pancreas during the development of Type 1 diabetes, highlighting their role in disease pathogenesis, potential of Treg-based therapies, and challenges in clinical applications.

This study found that CD1a-restricted CD4+ T cells responsive to lysyl-phosphatidylglycerol were more frequent in the blood of atopic dermatitis patients, suggesting a potential role in the disease's Th2-mediated pathology.

This article reviews the association between hepatitis C virus and systemic disorders like mixed cryoglobulinemia, highlighting potential autoimmune side effects from interferon-a2b treatments, and reports no new clinical results.

This study found that T cell-deficient mice developed distinct papilloma phenotypes after MmuPV1 infection, and hyperimmune sera transfer could prevent this infection.

This case report describes a previously healthy 3-year-old girl who developed scurvy symptoms not directly linked to vitamin C dietary deficiency, highlighting the potential for misdiagnosis in similar cases.

In this narrative review, researchers outlined the role of T cells in the autoimmune pathogenesis of alopecia areata and highlighted ongoing research into therapeutic pathways, beyond current JAK inhibitors, aimed at developing new treatments for the disease.