research Non-Clinical Safety Evaluation and Risk Assessment of Aleglitazar, a Dual PPAR α/γ Agonist, and Its Major Human Metabolite
Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.
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research Atlas of Geriatric Dermatology
The book details skin conditions in older adults, their link to mental health, cancer treatment importance, hair loss remedies, and managing autoimmune and itchy skin.
research Assessment of Serum Levels of Antigliadin Antibodies (IgG and IgA) in Patients with Alopecia Areata and Their Relation to Severity of the Disease
Higher antigliadin antibodies are linked to more severe alopecia areata, suggesting screening for celiac disease in these patients.
research A Computationally Inferred Regulatory Heart Aging Model Including Post-Transcriptional Regulations
Researchers created a model to understand heart aging, highlighting key genes and pathways, and suggesting miR-208a as a potential heart attack biomarker.
research The Role of Histone Demethylases in Disease
Histone demethylases play a key role in the development of many diseases and may be targets for treatment.
research Mesotherapy
Mesotherapy is a minimally invasive treatment with potential benefits and risks, requiring standardized practices and further investigation.
research Brown Adipose Tissue as an Innovative Approach for Polycystic Ovary Syndrome Treatment: A Narrative Review
More research is needed before using brown fat to treat polycystic ovary syndrome.
research Myotonic Dystrophy Type 1: Enhancing Patient Management Through Genetic and Multisystem Studies
There is no cure for myotonic dystrophy type 1, so treatment focuses on managing symptoms and complications.
research Assessment of Serum Levels of Antigliadin Antibodies (IgG and IgA) in Patients with Alopecia Areata and Their Relation to Severity of the Disease
Higher antigliadin antibody levels are linked to alopecia areata severity.
research Clinical and Molecular Genetic Studies in Hereditary Hair Loss
Researchers found a genetic link for hereditary hair loss but need more analysis to identify the exact gene.
research Subject Index
The document lists various dermatology topics, treatments, and diagnostic methods.
research Hair, Cutaneous Homeostasis, and Stem Cell Functions
Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.
research Impending Central Retinal Vein Occlusion And Granulomatous Uveitis In A Patient With Satoyoshi Syndrome
Satoyoshi syndrome can cause eye problems like uveitis and retinal vein issues.
research British Association of Dermatologists Guidelines on the Efficacy and Use of Acitretin in Dermatology
Acitretin is effective for severe skin conditions but has significant side effects and requires careful monitoring.
research Risk of Polycystic Ovary Syndrome in Women Exposed to Fine Air Pollutants and Acidic Gases: A Nationwide Cohort Analysis
Breathing in high levels of certain air pollutants significantly increases women's risk of developing Polycystic Ovary Syndrome.
research The Biological Actions of Dehydroepiandrosterone Involve Multiple Receptors
DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.
research Roles of MED1 in Quiescence of Hair Follicle Stem Cells and Maintenance of Normal Hair Cycling
MED1 is essential for normal hair growth and maintaining hair follicle stem cells.
research Generalized Alopecia with Vasculitis-Like Changes in a Dog with Babesiosis
The dog's skin and anemia issues returned after stopping treatment for Babesia gibsoni.
research Author Response: Quantitative Mapping of Human Hair Greying and Reversal in Relation to Life Stress
Hair can naturally regain color after greying, and this change may be linked to stress levels.
research Decision Letter: Quantitative Mapping of Human Hair Greying and Reversal in Relation to Life Stress
Hair can naturally regain color, and stress might influence greying and its reversal.
research Inactivation of the Vitamin D Receptor Enhances Susceptibility of Murine Skin to UV-Induced Tumorigenesis
Mice without the vitamin D receptor are more prone to UV-induced skin tumors.
research Telogen Effluvium: A Review of the Science and Current Obstacles
The document concludes that we need more research to understand Telogen Effluvium and find effective treatments.
research Serum Vitamin D3 Level in Patients with Female Pattern Hair Loss
Women with female pattern hair loss have lower Vitamin D3 levels.
research A Novel PLEC Nonsense Homozygous Mutation (c.7159G > T; p.Glu2387*) Causes Epidermolysis Bullosa Simplex with Muscular Dystrophy and Diffuse Alopecia: A Case Report
A new mutation in the PLEC gene causes a rare condition with skin blistering, muscle weakness, and hair loss.
research Alcohol Extract from Vernonia Anthelmintica Seed Counteracts Stress-Induced Murine Hair Follicle Growth Inhibition
Alcohol extract from Vernonia anthelmintica seeds may help treat stress-related hair loss.
research New Modalities in the Treatment of Refractory Alopecia Areata
New treatments focusing on immune pathways show promise for stubborn hair loss.
research Case Number 19 of Perforating Necrobiosis Lipoidica Worldwide
The document reports the first case of a rare skin condition in Colombia, the 19th case worldwide.
research Atrichia Caused by Mutations in the Vitamin D Receptor Gene Is a Phenocopy of Generalized Atrichia Caused by Mutations in the Hairless Gene
Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.
research Rare and Common Genetic Determinants of Metabolic Individuality and Their Effects on Human Health
Genetic variations greatly affect individual metabolism and can impact health and disease risk.
research Characterization of DNA Methylation and Screening of Epigenetic Markers in Polycystic Ovary Syndrome
DNA methylation changes in women with PCOS could be used as disease markers and suggest new treatment targets.