This study found that some white or grey human hairs can naturally regain pigmentation, suggesting a potential temporary reversibility of hair greying associated with stress and molecular changes.
16 citations
,
January 2018 in “International journal of trichology” This study observed that individuals with premature hair graying had lower levels of certain serum nutrients and lifestyle factors like stress and smoking may contribute; hair oiling appeared protective.
56 citations
,
November 2010 in “Pigment Cell & Melanoma Research” This article discusses the role of neurohormones and neuropeptides in hair follicle pigmentation and outlines promising neuroendocrinological strategies to address greying and damage, but reports no new clinical results.
152 citations
,
December 2003 in “Micron” This review discusses the development, regulation, and aging of the human hair follicle pigmentary system and suggests potential for reversing hair graying by manipulating follicle melanocytes in vitro, but reports no clinical results.
June 2025 in “Clinical Cosmetic and Investigational Dermatology” This study examined the factors contributing to gray hair, such as genetics and lifestyle, and found that while graying correlates with some health conditions, it is primarily a physiological process rather than a pathological one.