Impending Central Retinal Vein Occlusion And Granulomatous Uveitis In A Patient With Satoyoshi Syndrome

A 32-year-old woman with Satoyoshi syndrome, a rare autoimmune disease characterized by painful muscle spasms and generalized hair loss, developed impending central retinal vein occlusion (CRVO) secondary to granulomatous pan-uveitis. Her symptoms included sudden metamorphopsia and decreased visual acuity in the left eye, with extensive intraretinal hemorrhage and optic disc swelling observed. Treatment with increased prednisolone, oral aspirin, and kallidinogenase led to improvement in CRVO and visual acuity. However, she later developed angle nodules and uncontrolled intraocular pressure (IOP), necessitating trabeculotomy and trabeculectomy, which successfully reduced IOP. This case highlights the need for physicians to consider uveitis as a potential complication of Satoyoshi syndrome, as no previous reports have documented this association.