213 citations
,
June 2017 in “Rheumatology” This guideline outlines the management of systemic lupus erythematosus in adults but reports no new clinical findings.
144 citations
,
September 2006 in “Clinics in Dermatology” This article outlines manifestations of systemic lupus erythematosus, noting rapid joint symptom improvement with corticosteroids and antimalarial drug responsiveness for skin symptoms, and links anti-Ro with photosensitive rash and subacute lupus.
70 citations
,
February 2018 in “Seminars in Arthritis and Rheumatism” This study found that belimumab helped achieve low disease activity in over 40% of systemic lupus erythematosus patients in real-life settings, alongside reduced corticosteroid use and fewer flares.
52 citations
,
September 2021 in “Kidney International” In this report, a 23-year-old woman developed nephrotic syndrome and was diagnosed with lupus nephritis after receiving the first dose of the AstraZeneca COVID-19 vaccine, but causation is not established.
33 citations
,
August 2013 in “Lupus” This retrospective study observed that while systemic lupus erythematosus patients at King Fahd Hospital in eastern Saudi Arabia had similar clinical manifestations to those in other regions, there were differences in age of onset and sex distribution.
33 citations
,
May 1984 in “Journal of Pharmacy and Pharmacology” This study found that while systemic absorption of DHT from liposomes was negligible, the topical biological effect was weaker compared to DHT dissolved in acetone on the female hamster flank organ model.
30 citations
,
August 1998 in “International Journal of Dermatology” This study found that systemic corticosteroids led to satisfactory hair regrowth in 38.9% of severe alopecia areata patients, but hair fall occurred upon therapy discontinuation or tapering.
16 citations
,
April 2016 in “Medicine” This study described a case where lupus erythematosus panniculitis preceded the diagnosis of systemic lupus erythematosus, highlighting the need for regular follow-ups in LEP patients for potential SLE development.
16 citations
,
April 2006 in “Pediatrics International” This study reported that high-dose mizoribin therapy may be effective and safe for managing steroid-dependent pediatric systemic lupus erythematosus but requires monitoring of serum uric acid levels due to potential side effects.
15 citations
,
April 2016 in “Medicine” This study reports that systemic lupus erythematosus patients with Evans syndrome often exhibited photosensitivity, hypocomplementemia, and elevated serum IgG, while lupus nephritis was less common, suggesting distinct clinical features.
11 citations
,
February 2012 in “Pediatrics in Review” This article reviews systemic lupus erythematosus (SLE) and highlights the FDA approval of belimumab, marking the first new SLE treatment in nearly 50 years, but reports no new clinical trial results.
9 citations
,
August 2014 in “Lupus” This report presents a case of a 17-year-old woman with systemic lupus erythematosus and systemic vasculitis, highlighting the importance of early diagnosis and timely referral for intensive treatment.
7 citations
,
June 2018 in “Archives of Rheumatology” This case report describes a 37-year-old female with systemic lupus erythematosus who developed multiple eruptive dermatofibromas; lesions spontaneously resolved and highlight the rare coexistence of these conditions.
5 citations
,
January 2014 in “Indian Journal of Nephrology” This case report describes a 30-year-old woman with systemic lupus erythematosus who was successfully treated for recurrent hypokalemic periodic quadriparesis after being diagnosed with distal tubular acidosis.
4 citations
,
January 2015 in “Case Reports in Rheumatology” This case report highlights that early recognition and management of underlying connective tissue diseases, such as lupus, are essential in young patients presenting with unexpected symptoms like blurry vision and stroke signs.
3 citations
,
February 2021 in “Pediatric rheumatology online journal” This case study described a 16-year-old girl with systemic lupus erythematosus and trisomy X, suggesting that these patients might be at higher risk for avascular necrosis and osteoporosis.
3 citations
,
January 2022 in “Modern Rheumatology Case Reports” This case report details a rare instance of simultaneous onset of systemic lupus erythematosus and IgG4-related disease in a 73-year-old woman, where treatment improved symptoms by using high-dose glucocorticoids, hydroxychloroquine, and belimumab.
2 citations
,
October 2022 in “Rheumato” This case report from Tishreen Hospital highlights that although rare, cardiac tamponade and acute surgical abdomen due to acute peritonitis and ascites can occur concurrently as initial presentations of systemic lupus erythematosus.
This study observed that in a real-world clinical setting in Greece, belimumab effectively controlled disease activity in lupus patients and allowed for a reduction in glucocorticoid dosage, with more pronounced benefits seen in patients who were serologically active at the start of treatment.
This case report illustrates that prompt diagnosis and management of myositis, a rare manifestation of Systemic Lupus Erythematosus, can lead to favorable patient outcomes, as demonstrated by symptom resolution and normal electromyocardiography findings.
This case report highlights the diagnostic challenge of ANA-negative pediatric SLE in South Asia, emphasizing the need for comprehensive diagnostic criteria and clinical vigilance for early recognition and treatment.
June 2025 in “Neurology India” This case report describes a young girl with a rare association of anti-SRP positive necrotizing autoimmune myopathy and systemic lupus erythematosus, who responded well to corticosteroid treatment.
May 2025 in “The Journal of Rheumatology” This report describes two cases where female patients with chronic granulomatous disease developed manifestations of systemic lupus erythematosus, highlighting a rare association that may influence clinical evaluation and treatment planning.
August 2024 in “Intisari Sains Medis” In this case report, a 17-year-old girl with systemic lupus erythematosus presented with seizure-induced vocal cord palsy and gradually improved with treatment involving steroids, immunosuppressives, and speech therapy.
July 2024 in “Clinical Case Reports” In this case study, a 25-year-old presented with symptoms of lupus but tested negative for antinuclear antibodies, complicating diagnosis. The researchers emphasize that comprehensive diagnostic approaches, beyond ANA testing, are vital for effectively identifying and treating lupus nephritis to avoid serious outcomes.
This study provides insights into systemic lupus erythematosus patients' experiences with Anifrolumab, highlighting improvements in symptoms and health-related quality of life, despite ongoing daily life impacts.
December 2023 in “Curēus” In this case study, a 36-year-old female with severe lupus enteritis and intestinal pseudo-obstruction showed significant clinical improvement after treatment with intravenous methylprednisolone, hydroxychloroquine, and cyclophosphamide, highlighting the complexities and challenges in diagnosing and managing atypical lupus manifestations.
In this case report, a 19-year-old woman with systemic lupus erythematosus experienced significant improvement in neuropsychiatric symptoms, including psychosis and seizures, following treatment with high-dose corticosteroids, immunosuppressants, and antidepressants.
January 2022 in “Exclusive Real World Evidence Journal” This case report describes a 22-year-old female with systemic lupus erythematous whose primary symptom was vasculitic polyneuropathy, characterized by polyneuropathy and various positive autoimmune markers.
August 2021 in “BMJ Case Reports” This case report details a 27-year-old woman's diagnosis of systemic lupus erythematosus with immune-mediated intravascular haemolysis, which improved with steroid treatment.