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Male pattern baldness involves genetics, hormones, and needs better treatments.

Alopecia areata causes hair loss, has no cure, and various treatments exist.

Stem cell self-renewal is complex and needs more research for full understanding.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Cathepsin L is essential for normal hair growth and development.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.

Stress can stop hair growth in mice, and treatments can reverse this effect.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Liposomes could improve how skin care products work but are costly and not very stable.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.