research WNT10A Mutation Causes Ectodermal Dysplasia by Impairing Progenitor Cell Proliferation and KLF4-Mediated Differentiation
A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.
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30-60 / 1000+ results research Tretinoin Treatment of Fox-Fordyce Disease
Tretinoin may be effective for treating Fox-Fordyce disease.
research Percutaneous Absorption of Alpha-Tocopheryl Acetate
α-Tocopheryl acetate is well absorbed through healthy skin.
research Transdermal Delivery of Minoxidil with Block Copolymer Nanoparticles
Smaller nanoparticles improve minoxidil absorption through hair follicles.
research Genetics
Certain gene mutations can weaken the skin barrier and, when combined with environmental factors, lead to eczema and severe itching.
research Differential Molecular Signature of Dermal Papilla Cells from Balding and Non-Balding Scalp in 2D, 3D Culture and Co-Culture with Adipose-Derived Stem Cells
Dermal Papilla Cells grown in 3D and with stem cells better mimic natural hair growth conditions than cells grown in 2D.
research 3D-SeboSkin Model Application in Hidradenitis Suppurativa/Acne Inversa
The 3D-SeboSkin model effectively simulates Hidradenitis suppurativa and is useful for future research.
research Penetration and Distribution in Human Skin Focusing on the Hair Follicle
Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.
research Drug Permeation Through Hair Follicles: Importance and Potential
Hair follicles are important for drug delivery through the skin, but better methods are needed to understand and improve this process.
research Incidental Syringomas of the Scalp in a Patient with Scarring Alopecia
A woman with unexplained hair loss was found to have harmless skin tumors and a scarring hair loss condition, but the tumors didn't cause the hair loss.
research Multiple Apocrine Hidrocystomas Successfully Treated With Botulinum Toxin A
Botulinum toxin A effectively treated a man's facial cysts with no side effects and lasting results.
research Analysis of Gene Expression in Isolated Single Hair Follicles Using Semiquantitative Reverse-Transcriptase Polymerase Chain Reaction
Researchers developed a new way to measure gene activity in single hair follicles and found that a specific gene's activity changes with different amounts and times of treatment.
research Porokeratotic Adnexal Ostial Nevus: Review on the Entity and Therapeutic Approach
Laser treatments are the most effective for porokeratotic adnexal ostial nevus.
research Skin Biology: Understanding Biological Targets for Improving Appearance
The document concludes that a deeper understanding of skin aging and photodamage is needed to create better skin treatments.
research Molecular Pathology of Skin Adnexal Tumors
New markers and pathways have been found in skin tumors, helping better understand and diagnose them.
research Cutaneous Epithelial Stem Cells
Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.
research Lifting the Biofilm Lid on the Antibacterial and Antibiofilm Effects of Sodium Hypochlorite Against Staphylococcus Aureus in Atopic Dermatitis
Sodium hypochlorite can effectively prevent and remove Staphylococcus aureus biofilms in atopic dermatitis at high enough concentrations.
research Hyperplasia of Hair Follicles and Other Adnexal Structures in Cutaneous Lymphoproliferative Disorders
Hair follicle hyperplasia is common in both benign and malignant skin lymphoproliferative disorders, with a proposed new term "pseudolymphomatous adnexitis."
research Follicular Contact Dermatitis Revisited: A Review Emphasizing Neomycin-Associated Follicular Contact Dermatitis
Neomycin is a common cause of follicular contact dermatitis, which is treated by avoiding the allergen and using creams.
research Wound Healing Mechanisms
Wound healing is a complex process involving different cells and stages, leading to scar tissue formation and strength increase over time.
research Effect of Rubbing Application on the Skin Permeation of Active Ingredients from Lotion and Cream
Rubbing skin increases absorption of water-soluble drugs from lotions and creams, but not oil-soluble drugs.
research Chitosan Microparticles for Sustaining the Topical Delivery of Minoxidil Sulphate
Chitosan microparticles improve minoxidil sulphate delivery, potentially reducing daily applications.
research Aftermath of COVID-19 Through the Eyes of Trichoscopy
COVID-19 can cause significant hair loss.
research Epidermal Stem Cells in Orthopedic Regenerative Medicine
Epidermal stem cells show promise for treating orthopedic injuries and diseases.
research Evolving Approaches to Profiling the Microbiome in Skin Disease
New technologies help us better understand how skin microbes affect skin diseases.
research Madarosis, Milphosis, Eyelash Trichomegaly, and Dermatochalasis: Conditions Affecting the Periocular Area
The document concludes that changes in eyelashes and eyelid skin can indicate various local and systemic diseases.
research Epidermal Development in Mammals: Key Regulators, Signals from Beneath, and Stem Cells
Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
research Madarosis: A Marker of Many Maladies
Losing eyelashes or eyebrows can be a sign of many different health problems and needs a careful approach to treat effectively.
research Lineage Analysis of Epidermal Stem Cells
Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.
research Transfollicular Drug Delivery: Current Perspectives
Transfollicular drug delivery is promising but needs more research to improve and understand it better.