November 2015 in “European Journal of Inflammation” Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.
349 citations,
January 2005 in “The FASEB journal” Human skin can make serotonin and melatonin, which help protect and maintain it.
58 citations,
October 2016 in “Journal of Investigative Dermatology” Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.
1 citations,
February 2023 in “Daehan ui'sa hyeobhoeji/Daehan uisa hyeopoeji” Primary healthcare clinics are key in managing chemotherapy side effects using various medications and treatments.
June 2020 in “Journal of Investigative Dermatology” Tiny particles from skin cells can help activate hair growth.
September 2017 in “Plastic and Reconstructive Surgery – Global Open” Some migraine sufferers had no more headaches after getting a hair transplant.
March 2012 in “Journal of The American Academy of Dermatology” Higher levels of certain nerve-related proteins are linked to hair loss in women with scalp pain.
1 citations,
May 2012 in “Hair transplant forum international” Hair loss in men may be caused by inflammation triggered by hormones, and treatments reducing inflammation could potentially promote hair growth.
14 citations,
December 2021 in “International journal of molecular sciences” Growth hormone levels affect hair growth and loss, with too much causing excess hair and too little leading to hair loss.
10 citations,
August 2022 in “International Journal of Molecular Sciences” Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.
38 citations,
January 2017 in “PPAR Research” PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.
67 citations,
July 2016 in “Reviews in Endocrine and Metabolic Disorders” Stress can worsen skin conditions by affecting hormone levels and immune response.
15 citations,
January 2010 in “Experimental Dermatology” Hair loss in certain young mice is linked to a specific gene and can be caused by lack of iron.
Use the least toxic, most specific treatments for skin diseases, considering side effects and individual patient needs.
150 citations,
October 2010 in “The American Journal of Pathology” The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
24 citations,
May 1982 in “Biochemical Pharmacology” These drugs cause hair growth without affecting testosterone or adrenal hormones.
148 citations,
December 2018 in “Journal of autoimmunity” Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.
80 citations,
March 2008 in “Contact Dermatitis” Nearly half of the French individuals surveyed reported having a sensitive scalp, more common in women, often linked to hair loss and symptoms like itching, and triggered by factors including shampoos and pollution.
20 citations,
December 2013 in “Journal of Dermatology” UV-B light increases inflammation-related substances in acne-related skin cells.
6 citations,
April 2010 in “Journal of Dermatological Science” Laminin-511 may help promote hair growth, while laminin-332 does not affect hair loss.
1 citations,
August 2020 in “British Journal of Dermatology” Caffeine may protect hair follicles from stress-related hair loss.
47 citations,
September 2016 in “Reviews in endocrine and metabolic disorders” The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
39 citations,
March 2003 in “The Veterinary clinics of North America. Small animal practice/Veterinary clinics of North America. Small animal practice” Behavioral dermatology treats skin problems by considering both emotional and physical factors.
30 citations,
September 2003 in “Experimental Dermatology” Minoxidil helps prevent stress-caused hair loss in mice.
22 citations,
November 2007 in “Journal of Investigative Dermatology Symposium Proceedings” Hair growth and health are influenced by stress and hormones.
11 citations,
August 2018 in “Facial Plastic Surgery Clinics of North America” Adipose-derived stem cells show potential for skin rejuvenation and wound healing but require more research to overcome challenges and ensure safety.
7 citations,
July 2018 in “Journal of Functional Biomaterials” A new anti-baldness patch effectively treats hair loss by blocking enzymes linked to the condition.
March 2018 in “Nepal journal of dermatology, venereology & leprology” Hair loss linked to prostate enlargement; stress and family history important factors.
1113 citations,
August 1999 in “The New England Journal of Medicine” Hair follicle biology advancements may lead to better hair growth disorder treatments.
211 citations,
October 2001 in “The FASEB Journal” Noggin is necessary to start the hair growth phase in skin after birth.