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Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

Current treatments for alopecia show no significant long-term benefits.

Latanoprost can make eyelashes longer, thicker, and darker.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.

Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.

Hair follicles greatly increase caffeine absorption through the skin shortly after it's applied.

Iranian veterans exposed to sulfur mustard suffer from long-term skin itching and eye damage, with some risk of skin cancer and ongoing management challenges.

Male pattern baldness involves smaller hair follicles, larger oil glands, and other tissue changes, but not major blood supply issues.

New methods for skin and nerve regeneration can improve healing and feeling after burns.

Sponge helps heal wounds faster with less inflammation and better skin/hair growth.

Skin has specialized touch receptors that can tell different sensations apart.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.