33 citations
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December 2005 in “British Journal of Clinical Pharmacology” This study found that the Transdermal Delivery System efficiently delivers testosterone systemically and showed bioequivalent hormone concentrations to a known topical gel in healthy males.
22 citations
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March 2017 in “Transplant Infectious Disease” This case report describes successful treatment of generalized trichodysplasia spinulosa with leflunomide in a patient undergoing immunosuppressive therapy following solid organ transplantation.
April 2021 in “Journal of Investigative Dermatology” Blocking DPP4 can help prevent fat loss and skin fibrosis.
September 2018 in “Reactions Weekly” Two women had skin reactions from a hair loss treatment and got better after stopping use.
9 citations
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April 2021 in “Climacteric” This study provides a guideline for the safe and effective use of testosterone in women with hypoactive sexual desire disorder, recommending systemic transdermal testosterone for appropriate candidates while highlighting the importance of informed consent and monitoring due to unestablished long-term safety.
19 citations
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October 2023 in “Bioengineering” This study reviewed the efficacy of mechanical fractionation techniques to produce tissue stromal vascular fraction (tSVF) and found that tSVF injections are particularly effective for conditions like osteoarthritis and wound healing, with centrifugation before fractionation improving isolation efficiency regardless of preparation method.
November 2025 in “Journal of Diabetes Investigation” In this case study, a man with Werner syndrome and diabetes saw improved glycemic control and insulin resistance with dapagliflozin, suggesting its potential usefulness for managing diabetes in similar patients.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study in mice suggests that defects in hair follicles with mesenchymal TSC2 disruption may result from an impaired TGFβ1 response, indicating a potential novel treatment approach for tuberous sclerosis complex.
12 citations
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November 2014 in “Journal of Cutaneous Medicine and Surgery” This report describes a case where oral valganciclovir treatment led to improved skin texture and hair regrowth in a patient with trichodysplasia spinulosa.
11 citations
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July 2021 in “Genetics selection evolution” This study used whole-genome sequence data to identify numerous putative causal variants and genes affecting key wool traits and skin wrinkle in Merino sheep, highlighting their polygenic and pleiotropic nature.
April 2017 in “Journal of Investigative Dermatology” In this study, the authors concluded that the TS-associated polyomavirus may disrupt Wnt/β-catenin signaling, likely contributing to abnormal hair follicle formation in trichodysplasia spinulosa.
2 citations
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January 2018 in “International Journal of Trichology” This case report describes trichothiodystrophy in two sisters with only hair fragility, illustrating the condition's variable presentation and the importance of regular monitoring for potential associated impairments.
8 citations
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June 2016 in “Journal of Pediatric Orthopaedics B” This paper presents two cases of hair tourniquet syndrome and suggests washing baby socks inside out as a potential preventative measure.
This study found that ethanol and methanol extracts of Spirulina platensis did not exhibit cytotoxic activity on WiDr colon cancer cells.
2 citations
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January 2025 in “Advances in Skin & Wound Care” This study from ISTAP emphasizes the importance of preventing skin tears, particularly in vulnerable populations like older adults and neonates, and recommends strategies such as using silicone-based adhesives, emollient therapy, and maintaining a safe environment to reduce the risk of these injuries.
1 citations
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August 2025 in “Bioengineering” In this study, the combination of full-thickness skin column grafts and the TSN6 peptide improved wound healing quality in pigs by enhancing epidermal maturation compared to other treatments.
6 citations
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June 2014 in “PubMed” This study concluded that transurethral seminal vesiculoscopy combined with finasteride is a safe and effective treatment for recurrent hemospermia in the observed patients.
7 citations
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August 2016 in “Nursing for Women's Health” This article reviews the issue of hair-thread tourniquets in infants, emphasizing the importance of awareness for timely diagnosis and suggesting prevention strategies, but reports no new clinical results.
April 2012 in “Neuropediatrics” This article reviews the genetic and phenotypic characteristics of Trichothiodystrophy and discusses the associated DNA repair defects, but does not report new clinical findings.
1 citations
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January 2025 in “Therapeutic Advances in Drug Safety” This case report highlights the rare overlap of DRESS and Stevens-Johnson syndrome following antituberculosis treatment, emphasizing the critical importance of timely diagnosis and intervention to manage severe symptoms and prevent organ damage.
4 citations
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December 2021 in “Journal of clinical laboratory analysis” This study identified a splicing-site deletion in the DCAF17 gene associated with Woodhouse-Sakati syndrome in a large consanguineous pedigree, leading to typical phenotypic features.
3 citations
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August 2023 in “Drug safety” This source reports that trastuzumab deruxtecan improves outcomes in HER2-positive and HER2-low metastatic breast cancer, emphasizing the need for careful adverse event monitoring, particularly for interstitial lung disease, and managing emetic risk to maximize benefits.
April 2019 in “SUNScholar (Stellenbosch University)” The study investigated the efficacy of cognitive working memory training (CWMT) in reducing symptoms of hair-pulling disorder (HPD) in 30 participants. Over a 5-week period, participants underwent CWMT or a control condition involving puzzle building. Results showed that CWMT significantly decreased hair-pulling severity compared to the control at 5 weeks and 3 months, although the difference was not significant at 3 months. Working memory improved immediately post-training, but there were no baseline impairments in impulse control and emotional regulation, nor did CWMT impact these areas more than the control. Participants found CWMT feasible and acceptable, reporting increased openness about symptoms and feeling less isolated. The study concluded that CWMT was a feasible and effective intervention for HPD, warranting further research on its mechanisms and cost-efficiency in larger trials.
August 2024 in “American Journal of Medical Genetics Part A” In this case study, researchers detailed two Saudi cases of the ultra-rare Trichohepatoneurodevelopmental syndrome, identifying pathogenic variants in the CCDC47 gene and reinforcing a strong gene-disease association, which helps clarify the disorder's clinical features and genetic mutations.
7 citations
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August 2011 in “Giornale italiano di dermatologia e venereologia : organo ufficiale, Società italiana di dermatologia e sifilografia” This study found that the modified wash test demonstrated high reliability in diagnosing and assessing the severity of androgenetic alopecia and telogen effluvium.
July 2021 in “British Journal of Dermatology” This report describes a boy with ectodermal dysplasias who was genetically diagnosed due to newly discovered TSPEAR gene variants, which have now been associated with this condition.
3 citations
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January 2025 in “JID Innovations” This review reports that the unique tunnel structures in advanced hidradenitis suppurativa impair quality of life and resist biological therapy, with their formation involving complex cellular and molecular interactions, including microbial dysbiosis, all contributing to ongoing inflammation and scarring.
November 2022 in “Van Sağlık Bilimleri Dergisi” This study found no association between W locus allele variations and phenotypic traits like eye color, head spotting, and fur length in Turkish Van cats, suggesting other genetic factors should be explored.
January 2024 in “Wiadomości Lekarskie” This study discusses current surgical treatments for ischemic stroke, emphasizing the confirmed effectiveness of mechanical thrombectomy, and notes that advances in early recognition and rapid intervention at specialized stroke centers have significantly reduced mortality rates in recent decades.
10 citations
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November 2018 in “Nature Biotechnology” Drugmakers are optimistic about targeting the Wnt pathway for new treatments despite past challenges.