47 citations
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April 1978 in “Journal of Cutaneous Pathology” This study found that basal cell epithelioma resembles fetal primary epithelial germ based on specific cellular characteristics.
30 citations
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November 2020 in “Journal of Advanced Research” This study found that conditioned medium from keratinocytes improved the hair-inductive properties of cultured dermal papilla cells, suggesting potential for enhancing hair follicle regeneration.
8 citations
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September 1987 in “Acta Dermato Venereologica” In this study, the researchers used structural studies and molecular calculations to suggest that the enzyme in RXLI patient hair follicles is less efficient, rather than completely inactive.
20 citations
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September 2005 in “Endocrinology” This study identified novel selective androgen receptor modulators with enhanced in vivo pharmacological activity through structure-activity relationship analysis in castrated rats.
17 citations
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September 1953 in “Journal of Cell Science” This study found that the tetrazolium salt INT is the most effective for revealing dehydrogenase activity and certain histological structures in sheep and other mammals' skin.
January 2016 in “UNESP Institutional Repository (São Paulo State University)” This study suggests that the phenotype of melasma in women is influenced by structural and cellular changes across the epidermal-melanin unit, not just melanocyte hypertrophy, highlighting potential roles for dermal damage repair and fibroblast senescence.
1 citations
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December 2019 in “Clinical ophthalmology” This study found that bimatoprost eye drops increased eyelash length, thickness, pigmentation, and the number of eyelashes per follicle in rabbits, without causing inflammation.
3 citations
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January 2024 in “Poultry Science” This study demonstrated that FOXO3 influences feather follicle development in goose embryos by regulating the Wnt/β-catenin signaling pathway in dermal fibroblasts, resulting in changes to feather size and structure without altering follicle density.
2 citations
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November 2022 in “Acta crystallographica. Section B, Structural science, crystal engineering and materials./Acta crystallographica. Section B, Structural science, crystal engineering and materials” This study reports the synthesis and structural characterization of a novel dinuclear platinum(III) complex with potential antitumor and catalytic activity.
November 2025 in “Bioactive Materials” In this study, researchers developed a novel nucleic acid nanoparticle system incorporating quercetin, which they found enhances functional hair follicle regeneration and maintains epithelial structure stability in androgenetic alopecia by regulating hair follicle stem and dermal papilla cells.
December 2023 in “International journal of high dilution research” The study reported that mice receiving dynamized Melatonin 6 cH and Lissotriton 6 cH for 14 days exhibited improved coat health and increased endurance in forced swimming tests, with Melatonin-treated mice swimming 2.5 times longer and Lissotriton-treated mice 4 times longer than controls.
April 2020 in “Journal of the Endocrine Society” This study concluded that patients with type 3 acromegaly had higher comorbidities, greater disease activity, and increased mortality risk compared to those with type 1 and type 2 acromegaly, even after treatment adjustments.
4 citations
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August 2010 in “Acta Biologica Hungarica” This study found that novel compounds moderately inhibited 5α-reductase type 1 activity compared to finasteride, offering valuable data on structure-activity relationships.
In this study, researchers developed vegan exosome-like vesicles from microalgae that mimic mammalian exosomes, demonstrating promising in vitro, ex vivo, and clinical effects such as improved wrinkle depth and elasticity, making them a potential alternative in cosmetic applications.
98 citations
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December 2015 in “The Journal of Cell Biology” In this study, researchers found that the absence of type I or type II keratins in mice leads to severe skin barrier defects, highlighting keratins' crucial role in epidermal structure and function.
October 2025 in “Journal of Molecular Structure” Hyaluronic acid microneedles help deliver minoxidil derivatives effectively for hair regrowth.
December 1998 in “Acta Crystallographica Section C-crystal Structure Communications” This study describes the molecular conformation and intermolecular interactions in the crystalline structure of the compound C24H31BrO4.
4 citations
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September 2020 in “Andrologia” This study found that Origanum vulgare extract improved testicular structure and function in mice against finasteride-induced damage by enhancing antioxidant defense and modulating gene expression related to apoptosis.
April 2021 in “Indian Journal of Animal Research” This study examined the age-related changes in the dermal structure of goat skin, providing baseline data on its histomorphology, histochemistry, and histoenzymology.
7 citations
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May 2023 in “Nanomaterials” In this study on Danio rerio, researchers found that exposure to titanium dioxide nanoparticles did not affect embryonic development but altered the structure of male gonads, acting as potential endocrine disruptors with androgenic activity.
January 2026 in “Cutaneous and Ocular Toxicology” This study found that Yangxuebushen Decoction significantly promoted hair regrowth and improved hair follicle structure in a cyclophosphamide-induced alopecia mouse model by reducing inflammation, oxidative stress, and apoptosis.
November 2025 in “Journal of Investigative Dermatology” Dark skin has stronger barriers and structure due to specific gene activity.
April 2024 in “Advances in Redox Research” In this study, researchers found that polysulfides in human hair keratin contribute to hair strength and antioxidant capacity, with sulfur supplementation enhancing hair strength and cuticle structure amid oxidative stresses such as UV radiation.
101 citations
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December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reports the successful differentiation of mouse induced pluripotent stem cells into keratinocytes that can regenerate skin and its structures in an in vivo environment.
3 citations
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July 2020 in “Synthetic and Systems Biotechnology” This study found that the cytochrome P450 enzyme CYP-sb21 can hydroxylate cyclosporine A at multiple positions, reducing its immunosuppressive effects but retaining its hair growth-promoting side-effect, and suggests modifications to improve regioselectivity for commercial use.
The researchers reported that PEG-FGF2 conjugates, particularly Compound 6, significantly enhanced stability, proliferation, migration, and wound healing activity compared to native FGF2, despite some reduction in bioactivity near crucial binding domains.
69 citations
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January 1995 in “PubMed” This study suggests that the structure and function of mouse melanocytes in the epidermis and hair bulb are influenced by genetic factors and local tissue environment, including hormones and growth factors.
28 citations
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September 2021 in “EMBO reports” In this study, researchers used cryo-electron microscopy to reveal how the natural compound osthole inhibits TRPV3 channels by binding to specific sites, changing the channel's conformation.
12 citations
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October 1954 in “Textile Research Journal” This study found that alkali bromide solutions are absorbed into hair depending on salt activity, and the presence of the salt increases water absorption compared to normal conditions.
9 citations
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August 2005 in “Experimental Dermatology” In this study, the researchers report that a modified epimorphin-derived peptide shows potential for hair follicle regeneration, especially when used with 1% minoxidil in mice.