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The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Demodicosis is common and often missed, needing more recognition and treatment in skin care.

Palliative chemotherapy is cost-effective for advanced gastric and colorectal cancer but not clearly for pancreatic-biliary cancer.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

The conclusion is that the increasing use of drugs for lifestyle reasons is a complex issue influenced by corporate profit, consumer behavior, and the medicalization of everyday life, with potential negative effects on personal well-being.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.

New antifungal treatments for a children's scalp infection are effective and safe, but it's not decided if they will become the preferred option over the old treatment.

Hair mineral analysis might help diagnose diseases early, but standard methods are needed.

Vitamin D3 affects cell differentiation in specific skin areas.

Cancer development is like natural selection, involving mutated cells and environmental factors.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

The rise in tinea capitis cases in Stockholm is linked to increased African immigration.

The document concludes that more research is needed to understand how to treat muscle pain with drugs.

Disrupting Acvr1b in mice causes severe hair loss and thicker skin.

*Acorus calamus* has many medicinal benefits but needs more safety research.

Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.

S100A3 protein is crucial for hair shaft formation in mice.

50-nm nanoparticles are better at penetrating skin and targeting hair follicles for drug delivery than 100-nm ones.

Plant-based ingredients are effective and safe for modern skincare products.

New drug delivery methods can make natural compounds more effective and stable.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Sarcoptes scabiei infection causes significant health and behavior changes in wombats.

Minoxidil use during pregnancy may cause fetal harm.