An Interesting Case of Hepatic Adrenocortical Carcinoma

    July 2018 in “ DOAJ (DOAJ: Directory of Open Access Journals) ”
    Hikmat Permana, Gumgum Darmawan, Ervita Ritonga, Maya Kusumawati, Miftahurachman Miftahurachman, Nanny Natalia Mulyani Soetedjo
    TLDR A woman had a rare liver tumor causing male-like physical changes, highlighting the need for thorough checks when such symptoms appear.
    This document reported the first known case of hepatic adrenocortical carcinoma (ACC) in a 21-year-old Sundanese woman who presented with virilization symptoms, including hirsutism, deepening voice, and alopecia. Hormonal evaluations revealed significantly elevated levels of free testosterone, dehydroepiandrosterone sulfate, and estradiol, with low levels of LH and FSH. Imaging showed a large mass in the right liver lobe, and liver biopsy confirmed ACC. Despite treatment with spironolactone, there was no significant symptom improvement. The case highlighted the importance of thorough clinical evaluation and the potential for ectopic ACC to present similarly to adrenal gland tumors, with surgical resection being the primary treatment approach.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community I am having Success with RU58841 and 1mm Derma Roller

      in Microneedling  19 upvotes 2 years ago
      A user reported success with RU58841 and a 1mm derma roller for hair regrowth, noting significant improvement in hair density and reduced scalp visibility. They also mentioned using minoxidil and black castor oil in the past, with mixed results.

      community AA and Hirsutism but T levels are normal

      in Female  8 upvotes 3 years ago
      27-year-old female experiences aggressive hair thinning and hirsutism despite normal testosterone levels. Spironolactone and 2% minoxidil were ineffective; high DHEA sulfate levels may be the cause.

      community Does low HGH leading to hairloss?

      in Research/Science  12 upvotes 10 months ago
      The user experiencing diffuse hair loss is using various treatments including RU58841, finasteride, minoxidil with tretinoin, anti-hair loss shampoo, and microneedling, and is considering adding peptides TB500, BPC157, and GHK-Cu. They have low growth hormone levels and are questioning its impact on hair loss, while another user suggests androgenic alopecia and androgens are likely the main cause of hair loss.

      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 1 month ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community How does hair loss and recovery work?

      in Chat  12 upvotes 3 months ago
      Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

    Related Research

    1 / 1 results