research Subcellular Localization of the Five Members of the Human Steroid 5α-Reductase Family
All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.
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research Circumscribed Alopecia Areata Incognita
A rare form of alopecia causes hair thinning without bald spots and may be more common than thought, responding well to steroid treatment.
research Effects of Neonatal and Adolescent Neuroactive Steroid Manipulation on Locomotor Activity Induced by Ethanol in Male Wistar Rats
Changing neuroactive steroid levels early in life can affect how adult rats respond to alcohol's stimulating effects.
research Effect of Perfluorooctanesulfonate Exposure on Steroid Hormone Levels and Steroidogenic Enzyme Activities in Juvenile Silurana Tropicalis
PFOS exposure disrupts hormone levels and enzyme activities in juvenile frogs, affecting males and females differently.
research Candida Antigen Immunotherapy Versus Steroid in the Treatment of Alopecia Areata
Candida antigen is an effective and promising treatment for alopecia areata.
research Prophylactic Use of Shiunko in the Prevention of Radiation-Induced Scalp Dermatitis: A Preliminary Report
Shiunko ointment may help prevent scalp dermatitis during radiotherapy but doesn't stop hair loss.
research Superficial Cryotherapy Versus Intralesional Corticosteroid Injection in Alopecia Areata: A Comparative Clinical and Dermoscopic Study
Cryotherapy and steroid injections are similarly effective and safe for treating alopecia areata.
research Recent Advances in Thiasteroids Chemistry
New sulfur-containing steroid analogs show promise for more targeted medical treatments.
research Assessing Finasteride-Associated Sexual Dysfunction Using the FAERS Database
Finasteride use linked to increased risk of sexual dysfunction, especially in younger people.
research Repeated Finasteride Administration Induces Depression-Like Behavior in Adult Male Rats
Finasteride use can cause depression-like behavior in male rats.
research Finasteride for Androgenetic Alopecia Is Not Associated with Sexual Dysfunction: A Survey-Based, Single-Centre, Controlled Study
Finasteride use doesn't cause sexual dysfunction in men with hair loss.
research Mechanism of Action of Bolandiol (19-Nortestosterone-3β,17β-Diol), a Unique Anabolic Steroid with Androgenic, Estrogenic, and Progestational Activities
Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.
research Granulation Tissue Developed After Minor Trauma in a Psoriatic Patient on Long-Term Etretinate Therapy
Long-term etretinate use may cause delayed wound healing and extra tissue growth after injury.
research Triamcinolone Acetonide Intramuscularly: Effective Long-Acting Steroid Therapy in Dermatologic Disorders
Triamcinolone acetonide injections effectively treat skin disorders like eczema and psoriasis.
research Ovine Placental Steroid Synthesis and Metabolism in Late Gestation
Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.
research Adult-Onset Hair Loss in Chesapeake Bay Retrievers: A Clinical and Histological Study
Chesapeake Bay retrievers' hair loss is likely a breed-specific, hereditary condition linked to abnormal steroid levels and distinct skin changes.
research Brain Allopregnanolone Induces Marked Scratching Behavior in Diet-Induced Atopic Dermatitis Mouse Model
A brain-produced steroid causes increased scratching in mice with a skin condition similar to eczema.
research A Rare Case of an Androgen-Producing Stromal Luteoma of the Ovary in a Postmenopausal Woman, Diagnosed by Selective Venous Blood Sampling
Doctors used a special blood sampling technique to diagnose a woman's rare ovarian tumor that was producing male hormones.
research Activity of Steroid 4 and Derivatives 4a–4f as Inhibitors of the Enzyme 5α-Reductase Type 1
Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.
research Early Post-Natal Neuroactive Steroid Manipulation Modulates Ondansetron Effects on Initial Periods of Alcohol Consumption in Rats
Early changes in brain chemicals affect how a drug reduces alcohol intake in rats.
research Regulatory Effects of Thai Rice By-Product Extracts from Oryza Sativa L. Cv. Bue Bang 3 CMU and Bue Bang 4 CMU on Melanin Production, Nitric Oxide Secretion, and Steroid 5α-Reductase Inhibition
BB4CMU rice bran oil may help treat hair loss and gray hair.
research Steroid Responsive Mononeuritis Multiplex in the Cronkhite-Canada Syndrome
Steroid treatment improved both gut and nerve symptoms in a man with Cronkhite–Canada syndrome.
research The Use of Platelet-Rich Plasma in the Treatment of Alopecia - A Review of the Literature
Platelet-Rich Plasma therapy helps increase hair density and regrowth for some types of hair loss.
research The Use of 2D:4D Digit Ratio as a Predictor of Androgenetic Alopecia: A Review
Finger length ratios might help predict common hair loss.
research Histopathologic Prognostic Factors for Alopecia Areata Treated by Intralesional Corticosteroid
Certain scalp tissue features can predict how well alopecia areata responds to steroid injections.
research Hair Steroid Concentration Before and After the Beginning of the COVID-19 Pandemic in Preschoolers: The Moderating Effect of Family Characteristics
The COVID-19 pandemic did not significantly change stress levels in preschoolers, but higher-income families' children showed higher stress.
research Caffeic Acid N-[3,5-Bis(Trifluoromethyl)Phenyl] Amide as a Non-Steroidal Inhibitor for Steroid 5α-Reductase Type 1 Using a Human Keratinocyte Cell-Based Assay and Molecular Dynamics
Compound 4 is a promising treatment for hair loss with low toxicity.
research Clinical Use of Extracellular Vesicles in the Management of Male and Female Pattern Hair Loss: A Preliminary Retrospective Institutional Review Board Safety and Efficacy Study
Extracellular vesicles may effectively treat hair loss with minimal side effects.
research The Use of Microneedling Associated with Photobiomodulation in the Treatment of Male Androgenetic Alopecia: Case Series
Combining microneedling with light therapy increased hair density by 26% in men.
research Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men
Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.